Clay-mediated reaction of indoles with cyclohexane-1,3-diones: an expedient route to indolylcyclohexenones

Authors: Chakrabarty, Manas; Kundu, Taraknath; Harigaya, Yoshihiro

Source: Journal of Chemical Research, Volume 2004, Number 11, November 2004 , pp. 778-780(3)

Publisher: Science Reviews 2000 Ltd

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Abstract:

Indoles (1a-e) react with cyclohexane-1,3-diones (2a-c) on montmorillonite K10 clay at 60-70 °C to furnish the corresponding 3-(3′-indolyl)cyclohex-2-en-1-ones (5a-e, 6a-e, 7b-e) in 27-75% yields in 2.5-4 h.

Keywords: INDOLES, CYCLOHEXANE-1,3-DIONES, CLAY, INDOLYLCYCL

Document Type: Research article

DOI: http://dx.doi.org/10.3184/0308234043431528

Publication date: 2004-11-01

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