Water promoted iodotrimethyl silane reactions: reductive cleavage of isoxazolidines and 2,1-benzisoxazoles to γ-amino alcohols and o-aminobenzophenones

Authors: Boruah, Monalisa; Konwar, Dilip

Source: Journal of Chemical Research, Volume 2002, Number 12, 1 December 2002 , pp. 601-603(3)

Publisher: Science Reviews 2000 Ltd

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Abstract:

Water promoted iodotrimethyl silane [ITMS] reductively cleaved isoxazolidines and 2,1-benzisoxazoles to γ-amino alcohols and o-aminobenzophenones respectively at shorter times and in higher yields at room temperature.

Keywords: WATER PROMOTED IODOTRIMETHYLSILANE; ISOXAZOLIDINES; 2,1-BENZISOXAZOLES

Document Type: Short communication

DOI: http://dx.doi.org/10.3184/030823402103171186

Publication date: 2002-12-01

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  • The Journal of Chemical Research is a monthly journal which has a broad international authorship and publishes research papers and reviews in all branches of experimental chemistry.

    Recent papers have described new synthetic methods, new heterocyclic compounds, new natural products, and the inorganic chemistry of metal complexes. Now in its 34th year, the Journal of Chemical Research was established in 1977 as a joint venture by the British, French and German chemical societies and maintains the high standards set by the founding societies. Each paper is independently peer reviewed and only carefully evaluated contributions are accepted.

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