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Open Access An Approach to the Commercial Production of Highly Active Pharmaceutical Ingredients

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To meet the requirements for production of highly active pharmaceutical ingredients (API) new approaches and technical solutions are required. Prior to the design and construction of a new multipurpose manufacturing facility, a process study was performed to clarify the future needs. During the planning phase, concepts were defined and elaborated to meet production, cleaning, health and safety standards. The ideas were taken into account and a small-scale manufacturing facility was designed and realized accordingly.

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Document Type: Research Article

Affiliations: 1: F. Hoffmann-La Roche AG Grenzacherstrasse 124 CH-4058 Basel;, Email: [email protected] 2: F. Hoffmann-La Roche AG Grenzacherstrasse 124 CH-4058 Basel

Publication date: 2016-09-01

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  • International Journal for Chemistry and Official Membership Journal of the Swiss Chemical Society (SCS) and its Divisions

    CHIMIA, a scientific journal for chemistry in the broadest sense, is published 10 times a year and covers the interests of a wide and diverse readership. Contributions from all fields of chemistry and related areas are considered for publication in the form of Review Articles and Notes. A characteristic feature of CHIMIA are the thematic issues, each devoted to an area of great current significance.

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