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Open Access Surface-Enhanced Raman Scattering: An Emerging Label-Free Detection and Identification Technique for Proteins

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Abstract:

The detection and identification of biologically important molecules has critical importance in several fields such as medicine, biotechnology, and pharmacology. Surface-enhanced Raman scattering (SERS) is a powerful emerging vibrational spectroscopic technique that allows not only for the characterization, but also for the identification and detection of biomacromolecules in a very short time. In this review, efforts to utilize SERS for label-free protein detection and identification is summarized after a short introduction of proteins and the technique.

Keywords: Detection; Identification; Label-Free; Proteins; Surface-Enhanced Raman Scattering

Document Type: Research Article

DOI: http://dx.doi.org/10.1366/12-06895

Affiliations: Department Of Genetics And Bioengineering, Faculty Of Engineering, Yeditepe University, Atasehir, Istanbul 34755 Turkey

Publication date: April 1, 2013

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