Open Access Inductively Coupled Plasma‐Mass Spectrometry (ICP-MS) for Quantitative Analysis in Environmental and Life Sciences: A Review of Challenges, Solutions, and Trends

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This focal point review provides an overview of recent developments and capabilities of inductively coupled plasma mass spectrometry (ICP-MS) coupled with different separation techniques for applications in the fields of quantitative environmental and bio-analysis. Over the past years numerous technical improvements, which are highlighted in this review, have helped to promote the evolution of ICP-MS to one of the most versatile tools for elemental quantification. In particular, the benefits and possibilities of using state-of-the-art hyphenated ICP-MS approaches for quantitative analysis are demonstrated with a focus on environmental and bio-analytical applications.

Keywords: Chromatography; Environment; Heteroelements; Hyphenated techniques; ICP-MS; Inductively couple plasma-mass spectrometry; Isotope dilution; Proteomics; Quantification; Trace elements

Document Type: Research Article


Affiliations: Helmholtz Zentrum Geesthacht-Zentrum für Material und Küstenforschung, Department Marine Bioanalytical Chemistry, Max-Planck Str. 1, 21502 Geesthacht, Germany

Publication date: August 1, 2012

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