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Fluorocarbon Fiber-Optic Raman Probe for Non-Invasive Raman Spectroscopy

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Abstract:

We report the development of a novel fiber-optic Raman probe using a graded index fluorocarbon optical fiber. The fluorocarbon fiber has a simple Raman spectrum, a low fluorescence background, and generates a Raman signal that in turbid media serves as an intense reference Raman signal that corrects for albedo. The intensity of the reference signal can easily be varied as needed by scaling the length of the excitation fiber. Additionally, the fluorocarbon probe eliminates the broad silica Raman bands generated in conventional silica-core fiber without the need for filters.

Keywords: Cytop; Fiber-optic probe; Fluorocarbon fiber; Graded-index fiber; Non-invasive; Raman spectroscopy; Reference signal; Tissue albedo

Document Type: Research Article

DOI: http://dx.doi.org/10.1366/12-06592

Affiliations: Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109-1055, USA

Publication date: June 1, 2012

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