Determination of Ideal Offset for Spatially Offset Raman Spectroscopy

$29.00 plus tax (Refund Policy)

Buy Article:

Abstract:

A key design parameter in spatially offset Raman spectroscopy (SORS) is the choice of offset distance between the illumination and collection areas. To investigate this choice, we performed SORS measurements on a simple two-layer chemical phantom. We show that while the SORS ratio, or the ratio of signal from the bottom layer to the top layer, monotonically increases with spatial offset, the signal-to-noise ratio (SNR) does not. Specifically, we show that there exists a specific spatial offset that yields the best SNR for signal originating in the bottom layer of a two-layer sample. We also show that this SNR-optimal offset depends upon the strength of the particular Raman band. This work presents the considerations that should be taken into account when designing optical probes for use in SORS.

Keywords: SIGNAL-TO-NOISE RATIO; SORS; SPATIALLY OFFSET RAMAN SPECTROSCOPY; SPECTRAL UNMIXING

Document Type: Research Article

DOI: http://dx.doi.org/10.1366/000370210790571936

Affiliations: The Institute of Optics, University of Rochester, Rochester, New York 14627

Publication date: January 1, 2010

More about this publication?
Related content

Tools

Favourites

Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more