Multiway Calibration for Creatinine Determination in Human Serum Using the Jaffé Reaction

$29.00 plus tax (Refund Policy)

Buy Article:

Abstract:

Second-order calibration and multivariate spectroscopic-kinetic measurements in the visible region are proposed to improve the Jaffé method for creatinine assay. Analyses performed on synthetic mixtures containing bilirubin, glucose, and albumin confirm that second-order calibration is useful for creatinine determination in human serum. Quantitative determinations of creatinine with the parallel factor analysis (PARAFAC) and direct trilinear decomposition (TLD) methods were compared. It is shown that both methods can be used for creatinine determination in human serum, with an SEP (squared error of prediction) of 2.22 and coefficient of variability of 6.14% for PARAFAC, and an SEP of 2.38 and coefficient of variability of 6.57% for TLD.

Keywords: CREATININE ASSAY; JAFFE REACTION; PARAFAC; PARALLEL FACTOR ANAYLSIS; SECOND-ORDER CALIBRATION

Document Type: Research Article

DOI: http://dx.doi.org/10.1366/000370204322729478

Affiliations: Department of Physical Chemistry, Institute of Chemistry, Universidade Estadual de Campinas, SP, 13083-970, Brazil

Publication date: January 1, 2004

More about this publication?
Related content

Tools

Favourites

Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more