Skip to main content

Spectral Comparison of the Binding of Pyrene to beta-Cyclodextrin and beta-Cyclodextrin Derivatives

Buy Article:

$29.00 plus tax (Refund Policy)


beta-Cyclodextrin (beta-CD) is a seven-unit cyclic sugar molecule with a torroidal shape, a hydrophilic exterior, and a hydrophobic cavity. It has been hypothesized that pyrene (P) forms a P(beta-CD)2 complex in which the pyrene lies in between the two wide, or secondary, rims of the two beta-CDs. This dimer structure appears to be stabilized in the crystal state by hydrogen bonds between-OH groups on the rims of the adjacent beta-CDs. We have chosen to test this hypothesis by comparing the fluorescence properties of pyrene in the presence of substituted beta-CDs with these properties in the presence of beta-CD. These properties include the shape (I/III vibronic band ratio) and lifetime of pyrene fluorescence and the effect on the pyrene I/III ratio of additives such as an iodide ion and a fluorinated alcohol. The CD derivatives in this investigation include those with no wide rim substitution and those with substitution on both the wide and narrow rims of beta-CD. Our data indicate that the a P(beta-CD)2 complex forms only when there is no substitution on the wide rim, which confirms the proposed structure for this complex. Index Headings: Cyclodextrins; Pyrene; Guest/host complexes; Fluorescence.

Document Type: Research Article


Publication date: April 1, 2000

More about this publication?

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more