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Surface-Enhanced Raman Spectroscopy of Lipids on Silver Microprobes

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Abstract:

The surface-enhanced Raman scattering (SERS) spectra of model sebaceous gland secretions and their bacterially generated fatty acids are described. Long-chain fatty acids, their parent triglycerides, and long-chain hydrocarbons have characteristic SERS signatures that make them readily resolvable in heterogeneous mixtures. Silicon-substrate silver microprobes are shown to be useful for studying the spatial distribution of lipids and their corresponding fatty acids in nanoflow rate systems.

Keywords: SURFACE-ENHANCED RAMAN SPECTROSCOPY MICROELECTRODE LIPIDS FATTY ACIDS TRIGLYCERIDES SQUALENE SPATIALLY RESOLVED SPECTRA

Document Type: Research Article

DOI: http://dx.doi.org/10.1366/0003702981943338

Publication date: February 1, 1998

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