Surface-Enhanced Raman Spectroscopy of Lipids on Silver Microprobes

Authors: Weldon, Millicent K.; Zhelyaskov, Valentin R.; Morris, Michael D.

Source: Applied Spectroscopy, Volume 52, Issue 2, Pages 72A-73A and 175-321 (February 1998) , pp. 265-269(5)

Publisher: Society for Applied Spectroscopy

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Abstract:

The surface-enhanced Raman scattering (SERS) spectra of model sebaceous gland secretions and their bacterially generated fatty acids are described. Long-chain fatty acids, their parent triglycerides, and long-chain hydrocarbons have characteristic SERS signatures that make them readily resolvable in heterogeneous mixtures. Silicon-substrate silver microprobes are shown to be useful for studying the spatial distribution of lipids and their corresponding fatty acids in nanoflow rate systems.

Keywords: SURFACE-ENHANCED RAMAN SPECTROSCOPY MICROELECTRODE

Document Type: Research article

DOI: http://dx.doi.org/10.1366/0003702981943338

Publication date: 1998-02-01

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