Use of FT-IR Internal Reflection Spectroscopy in Combinatorial Chemistry

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Abstract:

Combinatorial chemistry technologies for new-lead discovery and lead optimization have recently captured the imagination of the drug-discovery community. With the use of solid-phase synthesis on polymer substrates, vast numbers of molecules, so-called chemical libraries, will be readily accessible by these combinatorial approaches as potential sources of new leads for drug discovery.

Keywords: Combinatorial chemistry; Internal reflection spectroscopy

Document Type: Short Communication

DOI: http://dx.doi.org/10.1366/0003702963906113

Affiliations: 1: Sandoz Pharma Ltd., CH-4002 Basel, Switzerland 2: Harrick Scientific Corporation, P.O. Box 1288, 88 Broadway, Ossining, New York 10562

Publication date: April 1, 1996

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