Determination of Nicotine by Surface-Enhanced Raman Scattering (SERS)

$29.00 plus tax (Refund Policy)

Buy Article:

Abstract:

The analytical application of surface-enhanced Raman spectroscopy (SERS) to the determination of nicotine is demonstrated. A simple spectroelectrochemical method using a copper or silver electrode as the SERS substrate has been developed, consisting of three steps: polishing a working electrode to a mirror finish; roughening the electrode in an electrolyte solution; and, finally, depositing the nicotine analyte onto the roughened electrode after immersion in a sample solution. During the reduction cycle, a large enhancement in nicotine Raman scattering is observed at the electrode surface. The intensity of the SERS signal on a silver electrode is linear with concentration from 10 to 900 ppb, with an estimated detection limit of 7 ppb. The total analysis time per sample is approximately five minutes. This procedure has been used to analyze the extract from a cigarette side-stream smoke sample (environmental tobacco smoke); the SERS results agree well with those of conventional gas chromatographic analysis.

Keywords: ETS; Environmental tobacco smoke; Nicotine; SERS; Surface-enhanced Raman

Document Type: Research Article

DOI: http://dx.doi.org/10.1366/0003702944027985

Affiliations: 1: Health Sciences Research Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6113 2: Health Sciences Research Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6113; current address: EIC Laboratories, Inc., Norwood, MA 02062

Publication date: November 1, 1994

More about this publication?
Related content

Tools

Favourites

Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more