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Biomedical Application of Near-Infrared Fourier Transform Raman Spectroscopy. Part I: The 1064-nm Excited Raman Spectra of Blood and Met Hemoglobin

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Abstract:

Raman spectroscopy, which has been employed extensively to study the structure and function of biological materials for the last two decades, also has considerable potential as a diagnostic and analytical tool in medicine. However, the medical application of Raman spectroscopy has been limited to some special topics such as lens research because most morbid materials emit strong fluorescence and are weak with respect to laser illumination. Fluorescence and decomposition, two major drawbacks of Raman spectroscopy which must be circumvented, have made its medical applications difficult.

Keywords: Biomedical application; FT-Raman; Hemoglobin; Near-infrared; Raman spectroscopy, Blood

Document Type: Short Communication

DOI: http://dx.doi.org/10.1366/0003702924125131

Affiliations: 1: Department of Chemistry, School of Science, Kwansei Gakuin University, Uegahara, Nishinomiya 662, Japan 2: Department of Biochemistry, The Jikei University School of Medicine, Nishi-Shin-bashi, Minato-ku, Tokyo 105, Japan 3: Analytical Instruments Division, JEOL Ltd., Akishima 196, Japan

Publication date: March 1, 1992

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