Raman Spectroscopic Identification of Uric-Acid-Type Kidney Stone

Authors: Kodati, Venkata Ramana1; Tu, Anthony T.1; Turumin, Jacob L.2

Source: Applied Spectroscopy, Volume 44, Issue 7, Pages 1101-1231 (August 1990) , pp. 1134-1136(3)

Publisher: Society for Applied Spectroscopy

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Abstract:

Kidney stones of the uric acid type were examined by Raman spectroscopy. The fingerprint pattern of the Raman spectra of these stones matched those of uric acid better than those of sodium urate. Although the Raman spectra of most stones were masked by the high fluorescence of the stones, with the use of a computer to correct the baseline, the Raman scattering bands became distinct. Uric acid has distinct Raman bands at 472, 562, 627, 784, 885, 999, 1039, 1122, 1234, 1288, 1046, 1499, 1595, and 1652 cm−1. The kidney stones examined also showed these bands, indicating that the stones were the uric acid type. Raman spectroscopy is a useful analytical tool for identifying the composition of kidney stones without much sample preparation.

Keywords: Kidney stone; Uric acid stone; Raman spectroscopy

Document Type: Research article

DOI: http://dx.doi.org/10.1366/0003702904086470

Affiliations: 1: Department of Biochemistry, Colorado State University, Fort Collins, Colorado 80523 2: Institute of Surgery, East-Siberian Department, Siberia Division Medical Science, U.S.S.R.

Publication date: 1990-08-01

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