A wide variety of fiber-optic sensors based on fluorescence have been developed for important applications in the last few years. Unfortunately, no systematic study describing an optimized design has appeared. A fiber-optic fluorescence sensor testbed was constructed, and different
optical designs and components were compared for sensitivity in detecting fluorescence. Different beamsplitters, launching objectives, filters, detectors, and configurations were evaluated on the basis of their measured signal-to-noise ratio in detecting 100 picomolar fluorescein. Sources
of noise and background were identified, and generally applicable means for minimizing them are described.
Bio/Molecular Engineering Branch, Code 6190, Naval Research Laboratory, Washington, D.C. 20375-5000 2:
Geo-Centers Inc., Newton Center, Massachusetts 02159
Publication date: January 1, 1990
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The Society publishes the internationally recognized, peer reviewed journal, Applied Spectroscopy, which is available both in print and online. Subscriptions are included with membership or can be purchased by institutional or corporate organizations. Abstracts may be viewed free of charge. Previously published as Bulletin (Society for Applied Spectroscopy)