Resonant Cell Laser-Based Photoacoustic Densitometer for Thin-Layer Chromatography

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Photoacoustic spectroscopy was applied to the in situ densitometry of thin-layer chromatographic plates. Fast laser-scanning detection with signal enhancement was demonstrated at a resonant frequency of the cell. The use of phase difference between signal and background provided higher signal-to-noise ratios. Detection limit for Orange G was 170 pg, and the analytical curve was linear over three orders of magnitude.

Keywords: Laser scanning technique; Photoacoustic spectroscopy; Thin-layer chromatography detector

Document Type: Research Article


Affiliations: Ames Laboratory-USDOE and Department of Chemistry, Iowa State University, Ames, Iowa 50011

Publication date: September 1, 1988

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