Protein Adsorption on the Surface of a Thin-Film Polymer Integrated Optical Waveguide

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Abstract:

Protein adsorption (fluorescein labeled gamma globulin, FITC-IgG) on the surface of poly(styrene) thin-film optical waveguides was fluorescently detected. The time course of adsorption, the FITC-IgG fluorescence spectra, and the surface concentration estimates are presented. The results demonstrate the potential use of polymer optical waveguides as integrated optic evanescent sensors.

Keywords: Fluorescence; Integrated optics; Spectroscopic techniques; Surface analysis

Document Type: Research Article

DOI: http://dx.doi.org/10.1366/0003702884428572

Affiliations: Department of Bioengineering and Center for Sensor Technology, University of Utah, Salt Lake City, Utah 84112

Publication date: January 1, 1988

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