A Practical Real-time Fourier Transform Infrared Detector for Liquid Chromatography

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A practical Fourier transform infrared system for real-time liquid chromatographic detection is described. Simple flowcell detection with automatic solvent subtraction is used, and detection of 500 ng of injected paraffin oil is demonstrated. Results from several chromatographic runs illustrate the system capability to serve as a real time infrared detector and simultaneously acquire infrared spectra.

Keywords: Fourier transform infrared spectrometry; Gel permeation chromatography; Infrared LC detector; LC-ir; Liquid chromatography; Molecular weight analysis; Polymer analysis; Steric exclusion chromatography

Document Type: Research Article

DOI: http://dx.doi.org/10.1366/000370278774331071

Affiliations: Nicolet Instrument Corporation, 5225 Verona Road, Madison, Wisconsin 53711

Publication date: September 1, 1978

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