Resonance Raman Spectrum of Cyanocobalamin (Vitamin B12)

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Resonance Raman spectra have recently been reported for a variety of biological materials including hemoglobin and cytochrome c. The resonance phenomenon leads to enhancement of intensity when molecules are excited by radiation of wavelength within that of an absorption band, and the effect provides a structural probe at low solution concentrations. We now report a resonance Raman study of cyanocobalamin (vitamin B12) in both solid and solution states together with a study of dicyanocobalamin and cyanoaquocobin-amide.

Keywords: Laser resonance Raman, Cyanocobalamin (vitamin B12)

Document Type: Short Communication


Affiliations: 1: School of Chemical Science and Technology, Kingston Polytechnic, Kingston Upon Thames, Surrey, United Kingdom 2: Biophysics Research Unit, King's College, Drury Lane, London, United Kingdom

Publication date: September 1, 1973

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