Skip to main content

Use of Resolidified Melts in Infrared Spectroscopy: Application to Polymorphism and Solvation Studies

The full text article is temporarily unavailable.

We apologise for the inconvenience. Please try again later.

A sample melt technique has been developed for the rapid identification by infrared spectra of polymorphs and solvates. Excellent spectra are obtained; no decomposition or rearrangements have been detected in studies with 35 compounds, which included 25 steroids. Resolidified melt spectra of known polymorphs have been identical. The problems of low solubility and unusable regions of the spectra encountered in solution studies are avoided. In the case of solvates, the solvent may be identified by its spectrum in the gaseous or liquid state, and the spectrum of the solvent-free compound may be determined on the resolidified melt.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Document Type: Research Article

Affiliations: The Upjohn Company, Kalamazoo, Michigan

Publication date:

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more