Controlling factors in bud and cambial activity and their relation to rooting in Douglas-fir, Pseudotsuga menziesii (Mirb.) Franco, stem cuttings were studied through two successive growth cycles. Stem cuttings of current season's growth were taken periodically from three 45- to 50-year-old sheared field-grown Douglas-fir trees. Cambium had no endogenously controlled dormancy. Auxin treatment increased cambial activity at the base of the cutting which subsequently increased rootability during pre- and post-dormancy. Rooting was least in October when bud dormancy was most pronounced. Auxin treatment with or without buds was not effective in stimulating rooting during true dormancy and cold treatment was required. No apparent relationship between stem cutting rootability and presence or absence of buds was observed. Forest Sci. 21:269-275.