Effect of Luffa echinata on Lipid Peroxidation and Free Radical Scavenging Activity

Authors: Kumar V.P.1; Shashidhara S.1; Kumar M.M.2; Sridhara B.Y.2

Source: Journal of Pharmacy and Pharmacology, Volume 52, Number 7, 1 July 2000 , pp. 891-894(4)

Publisher: Pharmaceutical Press

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Abstract:

The dried alcoholic (50%) extract of the plant Luffa echinata was investigated for inhibition of lipid peroxidation, for hydroxyl radical scavenging activity and interaction with 1,1-diphenyl-2-picrylhydrazyl stable free radical (DPPH).

It was found that the test extract exhibited a considerable inhibition of lipid peroxidation and possessed hydroxyl radical scavenging activity. Evaluation of antiradical scavenging activity showed significant interaction with DPPH.

These properties could be considered as a useful and exploitable combination for justi-fying the reported activity.

Document Type: Research article

DOI: 10.1211/0022357001774589

Affiliations: 1: Department of Pharmacognosy, Government College of Pharmacy, Bangalore, Karnataka 2: Institute of Animal Health & Veterinary Biologicals, Bangalore, Karnataka, India

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