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Zvi Griliches's contributions to the economics of technology and growth are identified. Included is a discussion of his contributions on: the determinants of differences in speed of adoption of innovations; the use of patents to measure technology; the private and social returns to R and spillover effects from R&D. Griliches's own evaluation of his research contribution is compared to the evaluation of others in the field, using as evidence citation counts of his works collected from the online Web of Science. Griliches's most important contribution is his 1957 Econometrica hybrid corn paper that is a foundation of the economics of technological innovation. Remarkably, the trend in annual citations to the paper has continued to increase for over 40 years. Finally, we summarize Griliches's most recent views on the practice of economics and on the most important unanswered questions in the economics of technology and growth.