This study was conducted to determine whether overweight and normal weight adolescent girls differ in family history of chronic noncommunicable diseases and to explore the difference in intake of vegetables, fruits, and high-fat foods among those girls. Data were collected in the outpatient clinic of National Nutrition Institute, Cairo, Egypt. The study was administered to a sample of 150 at-risk-of-overweight and overweight adolescent girls and 150 normal weight girls as control. Statistical analysis showed that overweight girls reported significantly higher incidence of diabetes mellitus in their families than normal weight girls. Analysis also showed that girls with family history of coronary heart disease had significantly higher intake of high-fat foods.