Single Dose Level Intradermal Skin Tests are not Diagnostic in Food Intolerance: A Double Blind Study

Author: Eaton, Keith1

Source: Journal of Nutritional & Environmental Medicine, Volume 14, Number 2, June 2004 , pp. 103-106(4)

Publisher: Routledge, part of the Taylor & Francis Group

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Abstract:

A double blind study was performed on 13 patients with food intolerance, confirmed by elimination dieting and repeated challenge. Intradermal testing was performed at 1:500, using 10 commonly reacting foods and 10 which rarely gave reactions, a total of 260 tests. As compared with the results of challenge, intradermal skin tests were assessed as 57.5% accurate. The results are compared with other studies, and whilst single strength intradermal testing cannot be put forward as a valid test for food intolerance it is suggested that apparent "false positive" responses may be due to a mechanism akin to atopy in IgE allergy.

Document Type: Research article

DOI: 10.1080/13590840410001734947

Affiliations: 1: The Princess Margaret Hospital Osborne Road WindsorBerkshire SL4 3SJ UK

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