Single Dose Level Intradermal Skin Tests are not Diagnostic in Food Intolerance: A Double Blind Study
Author: Eaton, Keith1
Source: Journal of Nutritional & Environmental Medicine, Volume 14, Number 2, June 2004 , pp. 103-106(4)
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Abstract:
A double blind study was performed on 13 patients with food intolerance, confirmed by elimination dieting and repeated challenge. Intradermal testing was performed at 1:500, using 10 commonly reacting foods and 10 which rarely gave reactions, a total of 260 tests. As compared with the results of challenge, intradermal skin tests were assessed as 57.5% accurate. The results are compared with other studies, and whilst single strength intradermal testing cannot be put forward as a valid test for food intolerance it is suggested that apparent "false positive" responses may be due to a mechanism akin to atopy in IgE allergy.Document Type: Research article
DOI: 10.1080/13590840410001734947
Affiliations: 1: The Princess Margaret Hospital Osborne Road WindsorBerkshire SL4 3SJ UK
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