In recent years, endocrine disruption has become a topic of increasing public and regulatory concern. This article outlines some of the current approaches being taken by both European regulatory agencies and industry working groups in order to devise suitable criteria for the identification
and management of endocrine disrupting chemicals. Plant protection products are likely to be impacted by recent changes which will create hazard based cut-off (ineligibility for registration) criteria for endocrine disrupting properties and so are used here to illustrate the approaches under
development. The paper briefly reviews potential impacts on European agriculture if certain chemicals and/or chemical classes are withdrawn from the market following implementation of the European cut-off criteria for endocrine disrupting properties.