Authors: Woodcock, N.P.; Sebag-Montefiore, D.; Mannion, R.A.; Alexander, D.J.; Miller, G.V.

Source: Annals of The Royal College of Surgeons of England, Volume 88, Number 3, May 2006 , pp. W7-W9(3)

Publisher: The Royal College of Surgeons of England

Abstract:

Necrotising fasciitis ('synergic gangrene') is a serious bacterial soft tissue infection with a rapidly progressive course and high mortality. It is caused by a variable combination of obligate anaerobes, streptococci, staphylococci, and Gram-negative bacilli. Histologically, it is characterised by obliterative endarteritis and thrombosis of the subcutaneous vessels, leukocyte infiltration, and fascial necrosis. It predominantly occurs in patients who are debilitated by a co-morbid condition such as diabetes, alcoholic liver disease, or intravenous drug use. We have described a case of necrotising fasciitis secondary to a locally advanced carcinoma of the lower rectum, as a likely consequence of perforation into the surrounding extraperitoneal tissues. The patient had no other identifiable predisposing factors.

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Document Type: Case report

DOI: http://dx.doi.org/10.1308/147870806X95249

Affiliations: 1: Department of Surgery, York Hospital, York, UK

Publication date: 2006-05-01

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• The Annals of The Royal College of Surgeons of England is the official journal of the College and is published eight times a year in January, March, April, May, July, September, October and November. The main aim of the journal is to publish high quality, peer-reviewed papers that relate to all branches of surgery.
  
  The Annals also includes letters and comments, a regular technical section, NICE news, controversial topics, CORESS feedback, book reviews and the best trainee presentations from England and Wales. The editorial board is composed of members of the College Council and experts from across the surgical specialties.
  
  Archive issues of the Annals of The Royal College of Surgeons of England are available via the PubMed Central database
  
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