Free Content Aloe vera: a systematic review of its clinical effectiveness

Authors: Vogler B.K.; Ernst E.

Source: British Journal of General Practice, Volume 49, Number 447, October 1999 , pp. 823-828(6)

Publisher: Royal College of General Practitioners

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Abstract:

Background. The use of aloe vera is being promoted for a large variety of conditions. Often general practitioners seem to know less than their patients about its alleged benefits.

Aim. To define the clinical effectiveness of aloe vera, a popular herbal remedy in the United Kingdom.

Method. Four independent literature searches were conducted in MEDLINE, EMBASE, Biosis, and the Cochrane Library. Only controlled clinical trials (on any indication) were included. There were no restrictions on the language of publication. All trials were read by both authors and data were extracted in a standardized, pre-defined manner.

Results. Ten studies were located. They suggest that oral administration of aloe vera might be a useful adjunct for lowering blood glucose in diabetic patients as well as for reducing blood lipid levels in patients with hyperlipidaemia. Topical application of aloe vera is not an effective preventative for radiation-induced injuries. It might be effective for genital herpes and psoriasis. Whether it promotes wound healing is unclear. There are major caveats associated with all of these statements.

Conclusion. Even though there are some promising results, clinical effectiveness of oral or topical aloe vera is not sufficiently defined at present.

Keywords: COMPLEMENTARY MEDICINE; ALOE VERA; REVIEW

Document Type: Review article

Publication date: 1999-10-01

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  • The British Journal of General Practice is an international journal publishing articles of interest to family practitioners and primary care researchers worldwide. The journal's 2010 Impact Factor is 2.07, making it the world's second most highly cited journal of general practice and primary health care.

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