Goal-oriented cognitive rehabilitation for an individual with Mild Cognitive Impairment: Behavioural and neuroimaging outcomes

Authors: Clare, Linda¹; van Paasschen, Jorien¹; Evans, Suzannah¹; Parkinson, Caroline¹; Woods, Robert¹; Linden, David¹

Source: Neurocase, Volume 15, Number 4, August 2009 , pp. 318-331(14)

Publisher: Psychology Press, part of the Taylor & Francis Group

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By this author: Clare, Linda ; van Paasschen, Jorien ; Evans, Suzannah ; Parkinson, Caroline ; Woods, Robert ; Linden, David

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Abstract:

An individual, goal-oriented cognitive rehabilitation intervention was conducted with AB, a 77-year-old woman with MCI. Outcomes were evaluated using a client-centred measure of goal achievement and an experimental associative learning task testing a skill practised in the intervention. Pre- and post-intervention fMRI scans were compared to examine changes in brain activation. Following intervention, AB showed improved performance on rehabilitation goals and on the associative learning task. There were significant decreases in brain activation in sensory areas and significant increases in memory-related areas. Both client-centred measures and fMRI may assist in detecting clinically-meaningful changes resulting from cognitive rehabilitation interventions.

Keywords: Cognitive plasticity; Cognition-focused intervention; Cognitive training; Goal setting; Memory; fMRI

Document Type: Research article

DOI: 10.1080/13554790902783116

Affiliations: 1: School of Psychology, Bangor University, Bangor, Gwynedd, UK