CASE REPORT: Postmortem Distribution of Tramadol, Amitriptyline, and Their Metabolites in a Suicidal Overdose

Authors: Bynum, Nichole D.1; Poklis, Justin L.1; Gaffney-Kraft, Maryanne1; Garside, Diana1; Ropero-Miller, Jeri D.2

Source: Journal of Analytical Toxicology, Volume 29, Number 5, July/August 2005 , pp. 401-406(6)

Publisher: Preston Publications

Key:
Free Content - Free Content
New Content - New Content
Subscribed Content - Subscribed Content
Free Trial Content - Free Trial Content

Abstract:

A case report involving a 34-year-old white male who was found dead at home by his roommate is presented. At the time of his death, he was being treated with tramadol/acetaminophen, metaxalone, oxycodone, and amitriptyline. The decedent's mother stated that he had been taking increasing amounts of pain medication in order to sleep at night. There were no significant findings at autopsy; however, toxicology results supported a cause and manner of death resulting from suicidal mixed tramadol and amitriptyline toxicity. This case reports the tissue and fluid distribution of tramadol, amitriptyline, and their metabolites in an acutely fatal ingestion in an effort to document concentrations of these analytes in 12 matrices with respect to one another to assist toxicologists in difficult interpretations.

Document Type: Research article

Affiliations: 1: Office of the Chief Medical Examiner, Chapel Hill, North Carolina 27599 2: RTI International, Research Triangle Park, North Carolina 27709

The full text electronic article is available for purchase. You will be able to download the full text electronic article after payment.

$43.00 plus tax      Refund Policy

 

OR

Back to top

Key:
Free Content - Free Content
New Content - New Content
Subscribed Content - Subscribed Content
Free Trial Content - Free Trial Content
Share this item with others: These icons link to social bookmarking sites where readers can share and discover new web pages.
Page Help Click here for Page Help
Shopping cart
Tools
Sign in






Need to register?
Sign up here
Text size: A | A | A | A