Free Content TECHNICAL NOTE: Stability of Ethanol in Postmortem Blood and Vitreous Humor in Long-Term Refrigerated Storage

Authors: Olsen T.; Hearn W.L.

Source: Journal of Analytical Toxicology, Volume 27, Number 7, October 2003 , pp. 517-519(3)

Publisher: Preston Publications

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Abstract:

Ethanol concentrations in postmortem blood and vitreous humor samples collected at the Miami-Dade Medical Examiner Department over 5-6 years ago were reexamined to assess whether vitreous humor is a more reliable specimen for the analysis of ethanol in samples stored long term. The average change in 50-mL polypropylene tubes containing blood was 0.06 gm/dL (35% loss). On the other hand, vitreous humor samples collected in 10-mL gray-top Vacutainer tubes yielded an average change of 0.01 gm/dL (6.1% loss). This study demonstrates that vitreous humor may be a reliable matrix for ethanol analysis following prolonged refrigerated storage of the samples.

Document Type: Research article

Affiliations: 1: Miami-Dade Medical Examiner Department, 1851 NW 10th Avenue, Miami, Florida 33136

Publication date: 2003-10-01

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  • The Journal of Analytical Toxicology (JAT), established in 1977 and published 9 times a year, is the international source covering a broad range of clinical, forensic, and industrial laboratory topics regarding the isolation, identification, and quantitation of potentially toxic substances.

    With an emphasis on practical application, JAT articles provide improved and novel techniques for use in clinical, forensic, workplace, sports testing (doping), and other toxicology laboratories. Articles describe newly developed methods in immunoassay testing, gas chromatography, liquid chromatography, mass spectrometry, atomic absorption spectrometry, solid and liquid phase extraction techniques, and other analytical approaches. Worldwide readership includes toxicologists, pathologists, chemists, clinicians, researchers, and educators working in medical examiner and law enforcement laboratories, hospitals, university and independent analytical laboratories, as well as the drug manufacturing industry.

    Each year in October, we publish a special issue from the Society of Forensic Toxicologists.

    JAT, as determined by ISI Citation Index, is one of the two most referenced international journals in forensic science.

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