IngentaConnect Oxytocin use in grand-multiparous patients: safety and complicati...

Authors: Ben-Aroya Z.¹; Yochai D.¹; Silberstein T.¹; Friger M.²; Hallak M.¹; Katz M.¹; Mazor M.¹

Source: Journal of Maternal-Fetal Medicine, Volume 10, Number 5, 1 October 2001 , pp. 328-331(4)

Publisher: Parthenon Publishing, part of the Taylor & Francis Group

Abstract:

Objective: To determine whether the use of oxytocin for the augmentation of labor in grandmultiparous women increases the risk of peripartum complications. Study design: During the years 1989–97, 11 075 grand-multiparous women delivered at our institution. In 424 grand-multiparous women, intravenous oxytocin was used for augmentation of labor. The control group consisted of the other 10 651 grand-multiparous women. All women were monitored for fetal heart rate and uterine contractions. We compared the rates of maternal and perinatal complications in these two groups by using chi

² analysis and Fisher's exact test when appropriate. Results: No significant differences were found between the oxytocin and the control groups in the rates of placental abruption, intrapartum fetal death, postpartum hemorrhage, uterine rupture, fetal distress, meconium-stained amniotic fluid, an Apgar score of less than 7 at 5 min, Cesarean section, retained placenta and vaginal and cervical lacerations. In contrast, a significant increase in the rate of vacuum deliveries was observed in patients given oxytocin as compared to controls (3.5% vs. 1.4%, respectively; p = 0.001). Conclusions: The use of oxytocin in the grand-multiparous parturient was a safe procedure with no significant increase in peripartum complications. However, a higher rate of vacuum deliveries was found.

Keywords: OXYTOCIN; GRAND-MULTIPAROUS WOMEN; LABOR MANAGEMENT; PERIPARTUM COMPLICATIONS

Language: English

Document Type: Research article

Affiliations: 1: Department of Obstetrics and Gynecology, Soroka University Medical Center, Beer-Sheva, Israel 2: Department of Epidemiology, Faculty of Health Sciences, Ben- Gurion University of the Negev, Beer-Sheva, Israel

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Oxytocin use in grand-multiparous patients: safety and complications