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Effectiveness of the Nicotine Inhaler for Smoking Cessation in an OTC Setting

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Objective: To evaluate the effectiveness of the Nicotrol® nicotine inhaler as an aid to smoking cessation in over-the-counter (OTC) versus health-care-provider (HCP) conditions.

Methods: Five hundred twenty healthy smokers were randomized to the treatment conditions and followed for a year.

Results: At most follow-up visits, abstinence rates for the HCP group were 2 to 3 times those observed in the OTC group. Abstinence at 1 year was .77% in the OTC condition versus 3.08% in the HCP condition [P<.01]. Inhaler use was low.

Conclusions: OTC nicotine inhaler appears to be ineffective, though quit rates are improved with HCP assistance.

Keywords: OTC; nicotine inhaler; nicotine replacement; smoking cessation

Document Type: Research Article


Affiliations: 1: Acting Associate Director, Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD. 2: Public Health, Arizona Cancer Center, University of Arizona. 3: Department of Family and Community Medicine, University of Arizona. 4: Mel and Enid Zuckerman Arizona College of Public Health, University of Arizona, Tucson, AZ.

Publication date: July 1, 2004

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  • The American Journal of Health Behavior seeks to improve the quality of life through multidisciplinary health efforts in fostering a better understanding of the multidimensional nature of both individuals and social systems as they relate to health behaviors.

    The Journal aims to provide a comprehensive understanding of the impact of personal attributes, personality characteristics, behavior patterns, social structure, and processes on health maintenance, health restoration, and health improvement; to disseminate knowledge of holistic, multidisciplinary approaches to designing and implementing effective health programs; and to showcase health behavior analysis skills that have been proven to affect health improvement and recovery.

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