Combining the Nicotine Inhaler and Nicotine Patch for Smoking Cessation
Abstract:Objective: To assess the combination of the nicotine inhaler and nicotine patch for smoking cessation. Methods: Thirty healthy volunteers were enrolled into this open-label clinical trial of the combined use of nicotine inhalers and patches (15mg/16hr) for 6 weeks, and then nicotine inhalers alone for an additional 6 weeks. Results: Compared to baseline, the percentage salivary cotinine replacement at the end of Week 1 was 74%. One week point abstinence at 6 weeks was 43.3% (95% CL=26%, 61%), and at 12 weeks was 30.0% (95% CL=14%, 46%). Conclusion: The combination of the nicotine inhaler and nicotine patch appears safe and tolerable when used for smoking cessation.
Document Type: Research Article
Affiliations: 1: Smoking Research Laboratory, Duke University and Durham VA Medical Centers, Department of Medicine, Duke University, Nicotine Research Program, Duke University and Durham VA Medical Centers. 2: Smoking Research Laboratory, Duke University and Durham VA Medical Centers. 3: Nicotine Research Program, Duke University and Durham VA Medical Centers, Department of Psychiatry, Duke University Durham, NC.
Publication date: March 1, 2000
The American Journal of Health Behavior seeks to improve the quality of life through multidisciplinary health efforts in fostering a better understanding of the multidimensional nature of both individuals and social systems as they relate to health behaviors.
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