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Combining the Nicotine Inhaler and Nicotine Patch for Smoking Cessation

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Abstract:

Objective: To assess the combination of the nicotine inhaler and nicotine patch for smoking cessation. Methods: Thirty healthy volunteers were enrolled into this open-label clinical trial of the combined use of nicotine inhalers and patches (15mg/16hr) for 6 weeks, and then nicotine inhalers alone for an additional 6 weeks. Results: Compared to baseline, the percentage salivary cotinine replacement at the end of Week 1 was 74%. One week point abstinence at 6 weeks was 43.3% (95% CL=26%, 61%), and at 12 weeks was 30.0% (95% CL=14%, 46%). Conclusion: The combination of the nicotine inhaler and nicotine patch appears safe and tolerable when used for smoking cessation.

Document Type: Research Article

DOI: http://dx.doi.org/10.5993/AJHB.24.2.4

Affiliations: 1: Smoking Research Laboratory, Duke University and Durham VA Medical Centers, Department of Medicine, Duke University, Nicotine Research Program, Duke University and Durham VA Medical Centers. 2: Smoking Research Laboratory, Duke University and Durham VA Medical Centers. 3: Nicotine Research Program, Duke University and Durham VA Medical Centers, Department of Psychiatry, Duke University Durham, NC.

Publication date: March 1, 2000

More about this publication?
  • The American Journal of Health Behavior seeks to improve the quality of life through multidisciplinary health efforts in fostering a better understanding of the multidimensional nature of both individuals and social systems as they relate to health behaviors.

    The Journal aims to provide a comprehensive understanding of the impact of personal attributes, personality characteristics, behavior patterns, social structure, and processes on health maintenance, health restoration, and health improvement; to disseminate knowledge of holistic, multidisciplinary approaches to designing and implementing effective health programs; and to showcase health behavior analysis skills that have been proven to affect health improvement and recovery.

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