DNA Vaccines: A Review

Author: Liu, Margaret A.

Source: Vaccines. Preventing Disease and Protecting Health, Vaccines. Preventing Disease and Protecting Health , pp. 245-255(11)

Publisher: Pan American Health Organization (PAHO)

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Abstract:

This article gives an overview of the mechanisms, preclinical and clinical efficacy of DNA vaccines, and points out the limitations of the first generation of such vaccines, and some of the promising second-generation developments. This technology is also being utilized in the field of protemics as a tool to elucidate the function of genes. The breath of applications for DNA vaccines (cancer, autoimmune and allergic diseases) is discussed. This is a chapter included in Vaccines. Preventing Disease and Protecting Health, a book that celebrates the ways in which vaccines have played a role in improving the health of the world's populations.

Keywords: Vaccines; Vaccine Development; Public Health; Immunization; Disease Prevention; DNA; DNA Vaccines

Document Type: Miscellaneous

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