Dengue Vaccines

Author: Vaugh, David

Source: Vaccines. Preventing Disease and Protecting Health, Vaccines. Preventing Disease and Protecting Health , pp. 200-206(7)

Publisher: Pan American Health Organization (PAHO)

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Abstract:

Departing from the increase that dengue disease has had dramatically since World War II the author informs about the dengue vaccine development efforts, as commercial vaccine developers have joined the effort to bring dengue vaccine to the market to protect both persons living in endemic areas and those traveling to those areas and some candidate vaccines (DENV-1, DENV-2, DENV-3, LAV-live attenuated vaccines, Live Chimera Vaccines, DNA vaccines) are in phase 2 testing and other vaccines moving to clinical trials. The success of other flavivirus vaccines (yellow fever, Japanese encephalitis) makes it possible to hope that a dengue vaccine is close at hand. This is a chapter included in Vaccines. Preventing Disease and Protecting Health, a book that celebrates the ways in which vaccines have played a role in improving the health of the world's populations.

Keywords: Vaccines; Vaccine Development; Public Health; Immunization; Disease Prevention; Dengue Vaccine; Dengue; DENV-1; DENV-2; DENV-3; DNA vaccines; Clinical trials