New Measles Vaccine Formulations and Delivery Systems and Their Potential Contribution to Reducing Measles Mortality Worldwide.

Authors: Teresa Aguado, Maria; Henao-Restrepo, Ana-Maria

Source: Vaccines. Preventing Disease and Protecting Health, Vaccines. Preventing Disease and Protecting Health , pp. 43-52(10)

Publisher: Pan American Health Organization (PAHO)

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Abstract:

This chapter reviews the case for new, needle-free measles vaccine delivery devices and new vaccine formulations. It focuses primarily on such needle-free vaccine delivery devices as jet injectors for delivering parenteral measles vaccine, and on alternative routes for measles mucosal immunization (aerosoldelivered and nasal vaccines). It also outlines the optimal profile for new products, summarizes the state of the art of these products, and considers their suitability and practicality for use in measles immunization programs, particularly in developing countries. Finally, this chapter presents an update on a special project that has been designated a high priority for WHO—the Measles Aerosol Project-. This is a chapter included in Vaccines. Preventing Disease and Protecting Health, a book that celebrates the ways in which vaccines have played a role in improving the health of the world's populations.

Keywords: Vaccines; Vaccine Development; Public Health; Public Health; Immunization; Disease Prevention; Measles; Measles Vaccine; Measles immunization; Aerosol immunization; Needle-free vaccine; Measles Aerosol Project