The Challenge of Epidemiology: Issues and Selected Readings

Preface. Introduction
pp. iv-ix(1)

Discussions
pp. 3-17(15)
Authors: Buck, Carol; Llopis, Alvaro; Nájera, Enrique; Terris, Milton

Airs, Waters, Places
pp. 18-19(2)
Author: Hippocrates,

An Inquiry into the Nature, Causes, and Cure of the Scurvy
pp. 20-23(4)
Author: Lind, James

About the Disease Commonly Called "Mal de la Rosa" in this Province
pp. 24-26(3)
Author: Casal, Gaspar

An Essay Concerning the Cause of the Endemial Colic of Devonshire
pp. 27-30(4)
Author: Baker, George

An Inquiry into the Causes and Effects of the Variolae Vaccinae
pp. 31-32(2)
Author: Jenner, Edward

A Description of the Physical and Moral State of Workers Employed in Cotton, Wool, and Silk Mills
pp. 33-36(4)
Author: Villerme, Louis R.

Observations Made During the Epidemic of Measles on the Faroe Islands in the Year 1846
pp. 37-41(5)
Author: Panum, Peter Ludwig

On the Mode of Communication of Cholera
pp. 42-45(4)
Author: Snow, John

The Etiology, Concept, and Prophylaxis of Childbed Fever
pp. 46-59(14)
Author: Semmelweis, Ignaz

The Mosquito Hypothetically Considered as the Agent of Transmission of Yellow Fever
pp. 60-66(7)
Author: Finlay, Carlos J.

Mortality of Miners: A Selection from the Reports and Writings of William Farr
pp. 67-71(5)

Notes on Verruga Peruana
pp. 72-74(3)
Authors: Carrión, Daniel

The Preservation of Health Amongst the Personnel of the Japanese Navy and Army
pp. 75-79(5)
Author: Takaki, Baron

A New Disease Entity in Man: A Report on Etiologic and Clinical Observations
pp. 80-81(2)
Author: Chagas, Carlos

Discussions
pp. 85-98(14)
Authors: Buck, Carol; Llopis, Alvaro; Nájera, Enrique; Terris, Milton

Considerations on Pellagra
pp. 99-102(4)
Author: Goldberger, Joseph

Cancer and Other Chronic Diseases in Massachusetts
pp. 103-111(9)
Authors: Bigelow, George H.; Lombard, Herbert L.

On the Epidemiology of Cancer
pp. 112-121(10)
Author: Greenwood, Major

Social Medicine and Public Health
pp. 122-124(3)
Author: Ryle, John A.

Sickness and Stress in Operational Flying
pp. 125-134(10)
Author: Reid, D.D.

Epidemiology: Old and New
pp. 135-141(7)
Author: Gordon, John E.

Infectious and Chronic Disease Epidemiology: Separate and Unequal?
pp. 142-145(4)
Author: Barrett-Connor, Elizabeth

Discussions
pp. 149-166(18)
Authors: Buck, Carol; Llopis, Alvaro; Nájera, Enrique; Terris, Milton

Statistics of Morbidity
pp. 167-175(9)
Author: Sydenstricker, Edgar

The Age Selection of Mortality from Tuberculosis in Successive Decades
pp. 176-179(4)
Author: Frost, Wade Hampton

Record Linkage
pp. 180-183(4)
Author: Dunn, Halbert L.

A Discussion of the Concepts of Incidence and Prevalence as Related to Epidemiologic Studies of Mental Disorders
pp. 184-197(14)
Author: Kramer, Morton

Nutrition, Growth, and Neurointegrative Development: An Experimental and Ecologic Study
pp. 198-222(25)
Authors: Cravioto, Joaquin; DeLicardie, Elsa R.; Birch, Herbert G.

Patterns of Urban Mortality
pp. 223-234(12)
Authors: Puffer, Ruth Rice; Griffith, G. Wynne

A Single Index of Mortality and Morbidity
pp. 235-242(8)
Author: Sullivan, Daniel F.

Potential Years of Life Lost Between Ages 1 and 70: An Indicator of Premature Mortality for Health Planning
pp. 243-251(9)
Authors: Romeder, J.M.; McWhinnie, J.R.

An Epidemiological Study of Endemic Typhus (Brill's Disease) in the Southeastern United States with Special Reference to Its Mode of Transmission
pp. 252-270(19)
Author: Maxcy, Kenneth F.

Endemic Fluorosis and Its Relation to Dental Caries
pp. 271-278(8)
Author: Dean, H. Trendley

The Racial and Social Incidence of Cancer of the Uterus
pp. 279-289(11)
Author: Kennaway, E.L.

Contribution to the Study of the Etiology and Prevention of Cancer of the Cervix of the Uterus
pp. 290-294(5)
Author: Gagnon, Fabien

Comparative Neutralizing Antibody Patterns to Lansing (Type 2) Poliomyelitis Virus in Different Populations
pp. 295-311(17)
Authors: Paul, John R.; Melnick, Joseph L.; Riordan, John T.

Prediction and Possible Prevention of Coronary Disease
pp. 312-318(7)
Author: Keys, Ancel

A Study of Environmental Factors in Carcinoma of the Cervix
pp. 319-349(31)
Authors: Wynder, Ernest L.; Cornfield, Jerome; Schroff, P.D.; Doraiswami, K.R.

Death by Liver Cirrhosis and the Price of Beverage Alcohol
pp. 350-357(8)
Author: Seeley, John R.

Epidemiological Studies of Cultural Change
pp. 358-367(10)
Authors: Cassel, John; Tyroler, Herman A.

Schizophrenia and Social Class
pp. 368-383(16)
Authors: Goldberg, E.M.; Morrison, S.L.

Epidemiology of Childhood Leukemia in Northumberland and Durham
pp. 384-392(9)
Author: Knox, George

Geographic and Climatic Aspects of Multiple Sclerosis: A Review of Current Hypotheses
pp. 393-400(8)
Authors: Kurland, Leonard T.; Reed, Dwayne

Natural Nidality of Transmissible Disease in Relation to Landscape Epidemiology of Zooanthroponoses
pp. 401-405(5)
Author: Pavlosky, E.

Observations on Recent Increase in Mortality from Asthma
pp. 406-414(9)
Authors: Speizer, F.E.; Doll, R.; Heaf, P.

The Cholera Near Golden Square
pp. 415-418(4)
Author: Snow, John

Milk-Borne Streptococcic Infections
pp. 419-425(7)
Author: Sullivan, Daniel F.

Congenital Cataract Following German Measles in the Mother
pp. 426-434(9)
Author: McAlister Gregg, N.

Rickettsialpox: A Newly Recognized Rickettsial Disease
pp. 435-441(7)
Authors: Greenberg, Morris; Pellitteri, Ottavio J.; Jellison, William L.

Outbreak of Paralysis in Morocco due to Ortho-cresyl Phosphate Poisoning
pp. 442-445(4)
Authors: Smith, Honor V.; Spalding, J.M.K.

Adenocarcinoma of the Vagina: Association of Maternal Stilbestrol Therapy with Tumor Appearance in Young Women
pp. 446-450(5)
Authors: Herbst, Arthur L.; Ulfelder, Howard; Poskanzer, David C.

Salmonellosis Associated with Marijuana: A Multistate Outbreak Traced By Plasmid Fingerprinting
pp. 451-457(7)
Authors: Taylor, David N.; Wachsmuth, I. Kaye; Shangkuan, Yung-Hui; Schmidt, Emmett V.; Barrett, Timothy J.; Schrader, Janice S.; Scherach, Charlene S.; McGee, Harry B.; Feldman, Roger A.; Brenner, Don J.

Tobacco Smoking as a Possible Etiologic Factor in Bronchiogenic Carcinoma: A study of Six Hundred and Eighty-Four Proved Cases
pp. 458-470(13)
Authors: Wynder, Ernest L.; Graham, Evarts A.

Cancer and Tobacco Smoking: A Preliminary Report
pp. 471-474(4)
Authors: Levin, Morton L.; Goldstein, Hyman; Gerhardt, Paul R.

Smoking and Carcinoma of the Lung: Preliminary Report
pp. 475-491(17)
Authors: Doll, Richard; Bradford Hill, A.

The Interrelation Between Uterine Cancer and Syphilis: A Patho-Demographic Study
pp. 492-499(8)
Authors: Røjel, Jørgen

Relationship Between Pregnancy Experience and the Development of Certain Neuropsychiatric Disorders in Childhood
pp. 500-505(6)
Authors: Lilienfeld, Abraham M.; Pasamanick, Benjamin; Rogers , Martha

A Survey of Childhood Malignancies
pp. 506-532(27)
Authors: Steward, Alice; Webb, Josefine; Hewitt, David

Statistical Aspects of the Analysis of Data from Retrospective Studies of Disease
pp. 533-553(21)
Authors: Mantel, Nathan; Haenszel , William

A Controlled Study of Fatal Automobile Accidents in New York City
pp. 554-565(12)
Authors: McCarroll, James R.; Haddon, William

Age at First Birth and Break Cancer Risk
pp. 566-577(12)
Authors: MacMajon, B.; Cole, P.; Lin, T.M.; Lowe, C.R.; Mirra, A.P.; Ravnihar, B.; Salber, E.J.; Valaoras, V.G.; Yuasa , S.

Increased Risk of Endometrial Carcinoma among Users of Conjugated Estrogens
pp. 578-583(6)
Authors: Ziel, Harry K.; Finkle, William D.

A Study of the Relation of Family Income and Other Economic Factors to Pellagra Incidence in Seven Cotton-Mill Villages of South Carolina in 1916
pp. 584-609(26)
Authors: Goldberger, Joseph; Wheeler, G.A.; Sydenstricker , Edgar

Mortality From Lung Cancer in Asbestos Workers
pp. 610-618(9)
Author: Doll , Richard

An Approach to Longitudinal Studies in a Community: The Framingham Study
pp. 619-630(12)
Authors: Dawber, Thomas R.; Kannel, William B.; Lyell , Lorna P.

Mortality in Relation to Smoking: Ten Years' Observations of British Doctors
pp. 631-667(37)
Authors: Doll, Richard; Bradford Hill, Austin

Final Report of a Prospective Study of Children Whose Mothers Had Rubella in Early Pregnancy
pp. 668-675(8)
Author: Sheridan, Mary D.

Radiation-related leukemia in Hiroshima and Nagasaki, 1946-1964 I. Distribution, Incidence, and Appearance Time
pp. 676-686(11)
Authors: Bizzozero, O. Joseph; Johnson, Kenneth G.; Ciocco, Antonio; Hoshino, Takashi; Itoga, Takashi; Toyoda, Shigeki; Kawasaki, Sho

Incidence and Prediction of Ischemic Heart Disease in London Busmen
pp. 687-698(12)
Authors: Morris, J.N.; Kagan, Aubrey; Pattison, D.C.; Gardner, M.J.; Raffle, P.A.B.

An Overview of the Risk Factors for Cardiovascular Disease
pp. 699-718(20)
Author: Kannel , William B.

Psychiatric Disorders in Foster Home Reared Children of Schizophrenic Mothers
pp. 719-725(7)
Author: Heston , Leonard L.

Pellagra Prevention by Diet among Institutional Inmates
pp. 726-730(5)
Authors: Goldberger, Joseph; Waring, C.H.; Tanner , W.F.

The Biology of Epidemics
pp. 731-746(16)
Author: Topley, W.W.C.

The Conclusion of a Ten-Year Study of Water Fluoridation
pp. 747-752(6)
Authors: Ast, David B.; Schlesinger , Edward R.

The Influence of Vitamin Supplementation of the Diets of Pregnant and Lactating Women on the Intelligence of Their Offspring
pp. 753-758(6)
Authors: Harrell, Ruth F.; Woodyard, Ella R.; Gates , Arthur I.

A Controlled Study of Three Methods of Prophylaxis against Streptococcal Infection in a Population of Rheumatic Children II. Results of the First Three Years of the Study, Including Methods for Evaluating the Maintenance of Oral Prophylaxis
pp. 759-765(7)
Authors: Feinstein, Alvan R.; Wood, Harrison F.; Epstein, Jeanne; Taranta, Angelo; Simpson, Rita; Tursky, Esther; Argyros, Thomas; Frieden, Julian; Haas, Raymond C.; Hirschfeld, Ilse; Lewis, Arthur J.; Manso, Carlos; Ulich , Konrad

The Dynamics of Malaria
pp. 766-779(14)
Authors: Macdonald, George; Cuellar, Caton B.; Foll, Cecil V.

Incidence of Cancer in Men on a Diet High in Polyunsaturated Fat
pp. 780-785(6)
Author: Sheridan , Mary D.

The Lipid Research Clinics Coronary Primary Prevention Trial Results I. Reduction in Incidence of Coronary Heart Disease
pp. 786-806(21)
Author: Lipid Research Clinics Program,

Discussions
pp. 809-828(20)
Authors: Buck, Carol; Llopis, Alvaro; Nájera, Enrique; Terris, Milton

Sick Individuals and Sick Populations
pp. 829-837(9)
Author: Rose, Geoffrey

Evaluation of 1954 Field Trials of Poliomyelitis Vaccine
pp. 838-854(17)
Authors: Francis, T.; Napier, J.A.; Voight, R.B.; Hemphill, R.M.; Wenner, H.A.; Korns, R.F.; Boisen, M.; Tochinsky, E.; Diamond, E.L.

The Surveillance of Communicable Diseases of National Importance
pp. 855-867(13)
Author: Langmuir, Alexander D.

Selective Epidemiologic Control in Smallpox Eradication
pp. 868-873(6)
Authors: Foege, William H.; Millar, J. Donald; Lane, J. Michael

Changes in Five-Year Breast Cancer Mortality in a Breast Cancer Screening Program
pp. 874-887(14)
Authors: Shapiro, Sam; Strax, Philip; Venet, Louis; Venet, Wanda

Does Screening by "Pap" Smears Help Prevent Cervical Cancer? A Case-Control Study
pp. 888-893(6)
Authors: Clarke, E.Aileen; Anderson, Terence W.

Measuring the Quality of Medical Care Through Vital Statistics Based on Hospital Service Areas: 1. Comparative Stud of Appendectomy Rates
pp. 894-902(9)
Author: Lembcke, Paul A.

Case-Fatality in Teaching and Non-Teaching Hospitals, 1956-1959
pp. 903-908(6)
Authors: Lipworth, L.; Lee, J.A.H.; Morris, J.N.

Rehabilitation of Nursing Home Residents
pp. 909-916(8)
Authors: Kelman, Howard R.; Muller, Jonas N.

The Iceberg: Completing the Clinical Picture in General Practice
pp. 917-922(6)
Author: Last, J.M.

The Burlington Randomized Trial of the Nurse Practitioner: Health Outcomes of Patients
pp. 923-929(7)
Authors: Sackett, David L.; Spitzer, Water O.; Gent, Michael; Roberts, Robin S.; Hay, W. Ian; Lefroy, Georgie M.; Sweeny, G. Patrick; Vandervlist, Isabel; Sibley, John C.; Chambers, Larry W.; Goldsmith, Charles H.; MacPherson, Alexander S.; McAuley, Ronald G.

Health Service "Input" and Mortality "Output" in Developed Countries
pp. 930-937(8)
Authors: Cochrane, A.L.; St. Leger, A.S.; Moore, F.

Ten-Year Results of a Randomized Clinical Trial Comparing Radical Mastectomy and Total Mastectomy With or Without Radiation
pp. 938-949(12)
Authors: Fisher, Bernard; Redmond, Carol; Fisher, Edwin R.; Bauer, Madeline; Wolmark, Norman; Wickerham, Lawrence; Deutsch, Melvin; Montague, Eleanor; Margolese, Richard; Foster, Roger

Failure of Extracranial-Intracranial Arterial Bypass to Reduce the Risk of Ischemic Stroke: Results of an International Randomized Trial
pp. 950-964(15)
Author: The EC/IC Bypass Study Group,

Discussions
pp. 967-985(19)
Authors: Buck, Carol; Llopis, Alvaro; Nájera, Enrique; Terris, Milton

Appendix: List of Contributors
pp. 986-989(4)