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The mission of Toxicological Sciences, the official journal of the Society of Toxicology, is to publish premier peer-reviewed, hypothesis-driven, original research articles in all areas of toxicology. Toxicological Sciences Manuscript Central (ToxSci MC), our online submission system, is located at http://mc.manuscriptcentral.com/toxsci. ToxSci MC facilitates convenient uploading of original and revised manuscripts, as well as online review-ing and intercommunication between authors, editors, and reviewers.

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Volume 125, Number 2, February 2012

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Accelerating the Development of 21st-Century Toxicology: Outcome of a Human Toxicology Project Consortium Workshop
pp. 327-334(8)
Authors: Stephens, Martin L.; Barrow, Craig; Andersen, Melvin E.; Boekelheide, Kim; Carmichael, Paul L.; Holsapple, Michael P.; Lafranconi, Mark

Identification of Urinary microRNA Profiles in Rats That May Diagnose Hepatotoxicity
pp. 335-344(10)
Authors: Yang, Xi; Greenhaw, James; Shi, Qiang; Su, Zhenqiang; Qian, Feng; Davis, Kelly; Mendrick, Donna L.; Salminen, William F.

Bioactivation versus Detoxication of the Urothelial Carcinogen Aristolochic Acid I by Human Cytochrome P450 1A1 and 1A2
pp. 345-358(14)
Authors: Stiborov, Marie; Levov, Kateina; Brta, Frantiek; Shi, Zhanquan; Frei, Eva; Schmeiser, Heinz H.; Nebert, Daniel W.; Phillips, David H.; Arlt, Volker M.

Parallel Biotransformation of Tetrabromobisphenol A in Xenopus laevis and Mammals: Xenopus as a Model for Endocrine Perturbation Studies
pp. 359-367(9)
Authors: Fini, Jean-Baptiste; Riu, Anne; Debrauwer, Laurent; Hillenweck, Anne; Le Mvel, Sbastien; Chevolleau, Sylvie; Boulahtouf, Abdelaye; Palmier, Karima; Balaguer, Patrick; Cravedi, Jean-Pierre; Demeneix, Barbara A.; Zalko, Daniel

Lentiviral-Mediated RNAi Knockdown Yields a Novel Mouse Model for Studying Cyp2b Function
pp. 368-381(14)
Authors: Damiri, Basma; Holle, Eric; Yu, Xianzhong; Baldwin, William S.

Aberrant Expression of miR-638 Contributes to Benzo(a)pyrene-Induced Human Cell Transformation
pp. 382-391(10)
Authors: Li, Daochuan; Wang, Qing; Liu, Caixia; Duan, Huawei; Zeng, Xiaowen; Zhang, Bo; Li, Xiaodong; Zhao, Jian; Tang, Shifu; Li, Zhifang; Xing, Xiumei; Yang, Ping; Chen, Liping; Zeng, Junling; Zhu, Xiaonian; Zhang, Shixin; Zhang, Zhengbao; Ma, Lu; He, Zhini; Wang, Erman; Xiao, Yongmei; Zheng, Yuxin; Chen, Wen

2-Amino-3-Methylimidazo[4,5-f]Quinoline (IQ) Promotes Mouse Hepatocarcinogenesis by Activating Transforming Growth Factor- and Wnt/-Catenin Signaling Pathways
pp. 392-400(9)
Authors: Xie, Xiao-Li; Wei, Min; Kakehashi, Anna; Yamano, Shotaro; Tajiri, Masaki; Wanibuchi, Hideki

An NF-BIndependent and Erk1/2-Dependent Mechanism Controls CXCL8/IL-8 Responses of Airway Epithelial Cells to Cadmium
pp. 418-429(12)
Authors: Cormet-Boyaka, Estelle; Jolivette, Kalyn; Bonnegarde-Bernard, Astrid; Rennolds, Jessica; Hassan, Fatemat; Mehta, Payal; Tridandapani, Susheela; Webster-Marketon, Jeanette; Boyaka, Prosper N.

Transcriptomic Concentration-Response Evaluation of Valproic Acid, Cyproconazole, and Hexaconazole in the Neural Embryonic Stem Cell Test (ESTn)
pp. 430-438(9)
Authors: Theunissen, Peter T.; Robinson, Joshua F.; Pennings, Jeroen L. A.; de Jong, Esther; Claessen, Sandra M. H.; Kleinjans, Jos C. S.; Piersma, Aldert H.

Selective Activation of Zebrafish Estrogen Receptor Subtypes by Chemicals by Using Stable Reporter Gene Assay Developed in a Zebrafish Liver Cell Line
pp. 439-449(11)
Authors: Cosnefroy, Anne; Brion, Franois; Maillot-Marchal, Emmanuelle; Porcher, Jean-Marc; Pakdel, Farzad; Balaguer, Patrick; At-Assa, Selim

Aerosolized ZnO Nanoparticles Induce Toxicity in Alveolar Type II Epithelial Cells at the Air-Liquid Interface
pp. 450-461(12)
Authors: Xie, Yumei; Williams, Nolann G.; Tolic, Ana; Chrisler, William B.; Teeguarden, Justin G.; Maddux, Bettye L.S.; Pounds, Joel G.; Laskin, Alexander; Orr, Galya

Zinc Oxide Nanoparticles Interfere With Zinc Ion Homeostasis to Cause Cytotoxicity
pp. 462-472(11)
Authors: Kao, Yi-Yun; Chen, Yi-Chun; Cheng, Tsun-Jen; Chiung, Yin-Mei; Liu, Pei-Shan

Cypermethrin Induces Astrocyte Apoptosis by the Disruption of the Autocrine/Paracrine Mode of Epidermal Growth Factor Receptor Signaling
pp. 473-487(15)
Authors: Maurya, Shailendra Kumar; Rai, Asit; Rai, Nagendra Kumar; Deshpande, Shreekant; Jain, Rajeev; Mudiam, Mohana Krishna Reddy; Prabhakar, Yenamandra S.; Bandyopadhyay, Sanghamitra

Dickkopf 1 Mediates Glucocorticoid-Induced Changes in Human Neural Progenitor Cell Proliferation and Differentiation
pp. 488-495(8)
Authors: Moors, Michaela; Bose, Raj; Johansson-Haque, Krishan; Edoff, Karin; Okret, Sam; Ceccatelli, Sandra

Subchronic Polychlorinated Biphenyl (Aroclor 1254) Exposure Produces Oxidative Damage and Neuronal Death of Ventral Midbrain Dopaminergic Systems
pp. 496-508(13)
Authors: Lee, Donna W.; Notter, Sarah A.; Thiruchelvam, Mona; Dever, Daniel P.; Fitzpatrick, Richard; Kostyniak, Paul J.; Cory-Slechta, Deborah A.; Opanashuk, Lisa A.

Mixed Inhibition of Adenosine Deaminase Activity by 1,3-Dinitrobenzene: A Model for Understanding Cell-Selective Neurotoxicity in Chemically-Induced Energy Deprivation Syndromes in Brain
pp. 509-521(13)
Authors: Wang, Yipei; Liu, Xin; Schneider, Brandon; Zverina, Elaina A.; Russ, Kristen; Wijeyesakere, Sanjeeva J.; Fierke, Carol A.; Richardson, Rudy J.; Philbert, Martin A.

Arsenic Exposure to Killifish During Embryogenesis Alters Muscle Development
pp. 522-531(10)
Authors: Gaworecki, Kristen M.; Chapman, Robert W.; Neely, Marion G.; DAmico, Angela R.; Bain, Lisa J.

Epigenetic Alterations in Sperm DNA Associated with Testicular Cancer Treatment
pp. 532-543(12)
Authors: Chan, Donovan; Delbs, Graldine; Landry, Mylne; Robaire, Bernard; Trasler, Jacquetta M.

Genomic Biomarkers of Phthalate-Induced Male Reproductive Developmental Toxicity: A Targeted RT-PCR Array Approach for Defining Relative Potency
pp. 544-557(14)
Authors: Hannas, Bethany R.; Lambright, Christy S.; Furr, Johnathan; Evans, Nicola; Foster, Paul M. D.; Gray, Earl L.; Wilson, Vickie S.

Divergent Electrocardiographic Responses to Whole and Particle-Free Diesel Exhaust Inhalation in Spontaneously Hypertensive Rats
pp. 558-568(11)
Authors: Lamb, Christina M.; Hazari, Mehdi S.; Haykal-Coates, Najwa; Carll, Alex P.; Krantz, Q. Todd; King, Charly; Winsett, Darrell W.; Cascio, Wayne E.; Costa, Daniel L.; Farraj, Aimen K.

The Role of MAPK and Nrf2 Pathways in Ketanserin-Elicited Attenuation of Cigarette SmokeInduced IL-8 Production in Human Bronchial Epithelial Cells
pp. 569-577(9)
Authors: Lau, Way Kwok Wai; Chan, Stanley Chi Hang; Law, Andrew Chi Kin; Ip, Mary Sau Man; Mak, Judith Choi Wo

Rat-Specific Decreases in Platelet Count Caused by a Humanized Monoclonal Antibody Against Sclerostin
pp. 586-594(9)
Authors: Rudmann, Daniel G.; Page, Todd J.; Vahle, John L.; Chouinard, Luc; Haile, Solomon; Poitout, Florence; Baskin, Gary; Lambert, Andr-Jean; Walker, Pamela; Glazier, Genevieve; Awori, Malaika; Bernier, Lise

Doxorubicin Increases Oxidative Metabolism in HL-1 Cardiomyocytes as Shown by 13C Metabolic Flux Analysis
pp. 595-606(12)
Authors: Strigun, Alexander; Wahrheit, Judith; Niklas, Jens; Heinzle, Elmar; Noor, Fozia

Exacerbation of Acetaminophen Hepatotoxicity by the Anthelmentic Drug Fenbendazole
pp. 607-612(6)
Authors: Gardner, Carol R.; Mishin, Vladimir; Laskin, Jeffrey D.; Laskin, Debra L.

CORRIGENDUM
pp. 613-613(1)

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