Toxicological Sciences

Genetic Polymorphism and ToxicologyWith Emphasis on Cytochrome P450
pp. 1-13(13)
Authors: Johansson, Inger; Ingelman-Sundberg, Magnus

Cardiotoxicity Associated with Targeting Kinase Pathways in Cancer
pp. 14-32(19)
Authors: Mellor, Howard R.; Bell, Alex R.; Valentin, Jean-Pierre; Roberts, Ruth R. A.

Acetaminophen-NAPQI Hepatotoxicity: A Cell Line Model System Genome-Wide Association Study
pp. 33-41(9)
Authors: Moyer, Ann M.; Fridley, Brooke L.; Jenkins, Gregory D.; Batzler, Anthony J.; Pelleymounter, Linda L.; Kalari, Krishna R.; Ji, Yuan; Chai, Yubo; Nordgren, Kendra K. S.; Weinshilboum, Richard M.

Estrogen-Like Activity of Perfluoroalkyl Acids In Vivo and Interaction with Human and Rainbow Trout Estrogen Receptors In Vitro
pp. 42-58(17)
Authors: Benninghoff, Abby D.; Bisson, William H.; Koch, Daniel C.; Ehresman, David J.; Kolluri, Siva K.; Williams, David E.

Prenatal Exposure to Flavonoids: Implication for Cancer Risk
pp. 59-67(9)
Authors: Vanhees, Kimberly; de Bock, Laura; Godschalk, Roger W. L.; van Schooten, Frederik J.; van Waalwijk van Doorn-Khosrovani, Sahar Barjesteh

Aryl Hydrocarbon Receptor Activation by TCDD Reduces Inflammation Associated with Crohn's Disease
pp. 68-78(11)
Authors: Benson, Jenna M.; Shepherd, David M.

Subtilase Cytotoxin Activates MAP Kinases through PERK and IRE1 Branches of the Unfolded Protein Response
pp. 79-86(8)
Authors: Zhao, Yang; Tian, Tian; Huang, Tao; Nakajima, Shotaro; Saito, Yukinori; Takahashi, Shuhei; Yao, Jian; Paton, Adrienne W.; Paton, James C.; Kitamura, Masanori

The Cytoprotective Effect of N-acetyl-L-cysteine against ROS-Induced Cytotoxicity Is Independent of Its Ability to Enhance Glutathione Synthesis
pp. 87-97(11)
Authors: Zhang, Fengjiao; Lau, Serrine S.; Monks, Terrence J.

Phospholipidosis Induced by PPAR Signaling in Human Bronchial Epithelial (BEAS-2B) Cells Exposed to Amiodarone
pp. 98-108(11)
Authors: Song, Mee; Kim, Youn-Jung; Ryu, Jae-Chun

Proteomics Investigations of Drug-Induced Hepatotoxicity in HepG2 Cells
pp. 109-122(14)
Authors: Van Summeren, Anke; Renes, Johan; Bouwman, Freek G.; Noben, Jean-Paul; van Delft, Joost H. M.; Kleinjans, Jos C. S.; Mariman, Edwin C. M.

Comparative Proteomics and Pulmonary Toxicity of Instilled Single-Walled Carbon Nanotubes, Crocidolite Asbestos, and Ultrafine Carbon Black in Mice
pp. 123-135(13)
Authors: Teeguarden, Justin G.; Webb-Robertson, Bobbie-Jo; Waters, Katrina M.; Murray, Ashley R.; Kisin, Elena R.; Varnum, Susan M.; Jacobs, Jon M.; Pounds, Joel G.; Zanger, Richard C.; Shvedova, Anna A.

Acute Imidazenil Treatment after the Onset of DFP-Induced Seizure Is More Effective and Longer Lasting than Midazolam at Preventing Seizure Activity and Brain Neuropathology
pp. 136-145(10)
Authors: Kadriu, Bashkim; Guidotti, Alessandro; Costa, Erminio; Davis, John M.; Auta, James

Changes in Dietary Iron Exacerbate Regional Brain Manganese Accumulation as Determined by Magnetic Resonance Imaging
pp. 146-153(8)
Authors: Fitsanakis, Vanessa A.; Zhang, Na; Avison, Malcolm J.; Erikson, Keith M.; Gore, John C.; Aschner, Michael

Human Prostaglandin H Synthase (hPHS)-1 and hPHS-2 in Amphetamine Analog Bioactivation, DNA Oxidation, and Cytotoxicity
pp. 154-162(9)
Authors: Ramkissoon, Annmarie; Wells, Peter G.

Manganese Uptake and Distribution in the Brain after Methyl Bromide-Induced Lesions in the Olfactory Epithelia
pp. 163-172(10)
Authors: Thompson, Khristy J.; Molina, Ramon M.; Donaghey, Thomas; Savaliya, Sandeep; Schwob, James E.; Brain, Joseph D.

Acute Functional Neurotoxicity of Lanthanum(III) in Primary Cortical Networks
pp. 173-183(11)
Authors: Gramowski, Alexandra; Jgelt, Konstantin; Schrder, Olaf H.-U.; Weiss, Dieter G.; Mitzner, Steffen

Dipentyl Phthalate Dosing during Sexual Differentiation Disrupts Fetal Testis Function and Postnatal Development of the Male Sprague-Dawley Rat with Greater Relative Potency than Other Phthalates
pp. 184-193(10)
Authors: Hannas, Bethany R.; Furr, Johnathan; Lambright, Christy S.; Wilson, Vickie S.; Foster, Paul M. D.; Gray, L. Earl

Application of Transcriptional Benchmark Dose Values in Quantitative Cancer and Noncancer Risk Assessment
pp. 194-205(12)
Authors: Thomas, Russell S.; Clewell, Harvey J.; Allen, Bruce C.; Wesselkamper, Scott C.; Wang, Nina Ching Y.; Lambert, Jason C.; Hess-Wilson, Janet K.; Zhao, Q. Jay; Andersen, Melvin E.

Interstrain Differences in the Liver Effects of Trichloroethylene in a Multistrain Panel of Inbred Mice
pp. 206-217(12)
Authors: Bradford, Blair U.; Lock, Eric F.; Kosyk, Oksana; Kim, Sungkyoon; Uehara, Takeki; Harbourt, David; DeSimone, Michelle; Threadgill, David W.; Tryndyak, Volodymyr; Pogribny, Igor P.; Bleyle, Lisa; Koop, Dennis R.; Rusyn, Ivan

Vascular Endothelial Growth Factor Receptor-1 Signaling Promotes Liver Repair through Restoration of Liver Microvasculature after Acetaminophen Hepatotoxicity
pp. 218-229(12)
Authors: Kato, Tetsuki; Ito, Yoshiya; Hosono, Kanako; Suzuki, Tatsunori; Tamaki, Hideaki; Minamino, Tsutomu; Kato, Shintaro; Sakagami, Hiroyuki; Shibuya, Masabumi; Majima, Masataka

Considerations for the Implausibility of Leukemia Induction by Formaldehyde
pp. 230-232(3)
Authors: Thompson, Chad M.; Grafstrm, Roland C.

Further Considerations for the Implausibility of Leukemia Induction by Formaldehyde
pp. 233-233(1)
Authors: Lu, Kun; Moeller, Benjamin C.; Swenberg, James A.