Toxicological Sciences

Arsenolysis and Thiol-Dependent Arsenate Reduction
pp. 249-252(4)
Author: Thomas, David J.

Manipulation of Regulatory T-Cell Function by Immunomodulators: A Boon or a Curse?
pp. 253-262(10)
Authors: Fort, Madeline M.; Narayanan, Padma K.

Effects of Maternal Smoking and Exposure to Methylmercury on Brain-Derived Neurotrophic Factor Concentrations in Umbilical Cord Serum
pp. 263-269(7)
Authors: Spulber, Stefan; Rantamki, Tomi; Nikkil, Outi; Castrn, Eero; Weihe, Pl; Grandjean, Philippe; Ceccatelli, Sandra

Polynucleotide Phosphorylase and Mitochondrial ATP Synthase Mediate Reduction of Arsenate to the More Toxic Arsenite by Forming Arsenylated Analogues of ADP and ATP
pp. 270-281(12)
Authors: Nmeti, Balzs; Regonesi, Maria Elena; Tortora, Paolo; Gregus, Zoltn

Toxicokinetics of the Flame Retardant Hexabromocyclododecane Gamma: Effect of Dose, Timing, Route, Repeated Exposure, and Metabolism
pp. 282-293(12)
Authors: Szabo, David T.; Diliberto, Janet J.; Hakk, Heldur; Huwe, Janice K.; Birnbaum, Linda S.

Characterization of Cellular Uptake of Perfluorooctanoate via Organic Anion-Transporting Polypeptide 1A2, Organic Anion Transporter 4, and Urate Transporter 1 for Their Potential Roles in Mediating Human Renal Reabsorption of Perfluorocarboxylates
pp. 294-302(9)
Authors: Yang, Ching-Hui; Glover, Kyle P.; Han, Xing

Methanol Induces a Discrete Transcriptional Dysregulation that Leads to Cytokine Overproduction in Activated Lymphocytes
pp. 303-313(11)
Authors: Dsy, Olivier; Carignan, Damien; Caruso, Manuel; de Campos-Lima, Pedro O.

Innate Immunity and Inflammation in Sepsis: Mechanisms of Suppressed Host Resistance in Mice Treated with Ethanol in a Binge-Drinking Model
pp. 314-324(11)
Authors: Pruett, Stephen B.; Fan, Ruping; Cheng, Bing; Glover, Mitzi; Tan, Wei; Deng, Xiaomin

Developmental Immunotoxicity of Methylmercury: The Relative Sensitivity of Developmental and Immune Parameters
pp. 325-335(11)
Authors: Tonk, Elisa C. M.; de Groot, Didima M. G.; Penninks, Andr H.; Waalkens-Berendsen, Ine D. H.; Wolterbeek, Andr P. M.; Slob, Wout; Piersma, Aldert H.; van Loveren, Henk

Tracking Human Contact Allergens: From Mass Spectrometric Identification of Peptide-Bound Reactive Small Chemicals to Chemical-Specific Naive Human T-Cell Priming
pp. 336-347(12)
Authors: Dietz, Lisa; Esser, Philipp R.; Schmucker, Sonja S.; Goette, Irina; Richter, Anne; Schnlzer, Martina; Martin, Stefan F.; Thierse, Hermann-Josef

Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening
pp. 348-358(11)
Authors: Rotroff, Daniel M.; Wetmore, Barbara A.; Dix, David J.; Ferguson, Stephen S.; Clewell, Harvey J.; Houck, Keith A.; LeCluyse, Edward L.; Andersen, Melvin E.; Judson, Richard S.; Smith, Cornelia M.; Sochaski, Mark A.; Kavlock, Robert J.; Boellmann, Frank; Martin, Matthew T.; Reif, David M.; Wambaugh, John F.; Thomas, Russell S.

Glycosylation Protects Proteins against Free Radicals Generated from Toxic Xenobiotics
pp. 359-374(16)
Authors: Martnek, Vclav; Sklen, Jan; Dransk, Martin; ulc, Miroslav; Hofbauerov, Kateina; Bezouka, Karel; Frei, Eva; Stiborov, Marie

Toxicoepigenetic Alteration of the Kidney Injury Molecule 1 Gene in Gentamicin-Exposed Rat Kidney
pp. 375-380(6)
Authors: Chen, Feifei; Smith, Roger; Gu, Yi-Zhong; Collins, Nathaniel D; Nioi, Paul

Time Series Analysis of Benzo[A]Pyrene-Induced Transcriptome Changes Suggests That a Network of Transcription Factors Regulates the Effects on Functional Gene Sets
pp. 381-392(12)
Authors: van Delft, Joost H. M.; Mathijs, Karen; Staal, Yvonne C. M.; van Herwijnen, Marcel H. M.; Brauers, Karen J. J.; Boorsma, Andr; Kleinjans, Jos C. S.

CH223191 Is a Ligand-Selective Antagonist of the Ah (Dioxin) Receptor
pp. 393-403(11)
Authors: Zhao, Bin; DeGroot, Danica E.; Hayashi, Ai; He, Guochun; Denison, Michael S.

Genome-wide Analysis of DNA Methylation and Gene Expression Changes in the Mouse Lung following Subchronic Arsenate Exposure
pp. 404-417(14)
Authors: Boellmann, Frank; Zhang, Lu; Clewell, Harvey J.; Schroth, Gary P.; Kenyon, Elaina M.; Andersen, Melvin E.; Thomas, Russell S.

Neurotoxicity of Fungal Volatile Organic Compounds in Drosophila melanogaster
pp. 418-426(9)
Authors: Inamdar, Arati A.; Masurekar, Prakash; Bennett, Joan Wennstrom

Enhanced Learning Deficits in Female Rats Following Lifetime Pb Exposure Combined with Prenatal Stress
pp. 427-438(12)
Authors: Cory-Slechta, Deborah A.; Stern, Sander; Weston, Doug; Allen, Joshua L.; Liu, Sue

Toxicant-Induced Leakage of Germ CellSpecific Proteins from Seminiferous Tubules in the Rat: Relationship to Blood-Testis Barrier Integrity and Prospects for Biomonitoring
pp. 439-448(10)
Authors: Elkin, Naomi D.; Piner, Jacqui A.; Sharpe, Richard M.

Suppression of Radiation-Induced Testicular Germ Cell Apoptosis by 2,5-Hexanedione Pretreatment. I. Histopathological Analysis Reveals Stage Dependence of Attenuated Apoptosis
pp. 449-456(8)
Authors: Yamasaki, Hideki; Sandrof, Moses A.; Boekelheide, Kim

Suppression of Radiation-Induced Testicular Germ Cell Apoptosis by 2,5-Hexanedione Pretreatment. II. Gene Array Analysis Reveals Adaptive Changes in Cell Cycle and Cell Death Pathways
pp. 457-465(9)
Authors: Campion, Sarah N.; Houseman, E. Andres; Sandrof, Moses A.; Hensley, Janan B.; Sui, Yunxia; Gaido, Kevin W.; Wu, Zhijin; Boekelheide, Kim

Suppression of Radiation-Induced Testicular Germ Cell Apoptosis by 2,5-Hexanedione Pretreatment. III. Candidate Gene Analysis Identifies a Role for Fas in the Attenuation of X-rayInduced Apoptosis
pp. 466-474(9)
Authors: Campion, Sarah N.; Sandrof, Moses A.; Yamasaki, Hideki; Boekelheide, Kim

Modified Expression of Several Sperm Proteins after Chronic Exposure to the Antiandrogenic Compound Vinclozolin
pp. 475-484(10)
Authors: Auger, Jacques; Eustache, Florence; Maceiras, Paula; Broussard, Cdric; Chafey, Philippe; Lesaffre, Corinne; Vaiman, Daniel; Camoin, Luc; Auer, Jana

Comprehensive Investigation of Hydroxypropyl Methylcellulose, Propylene Glycol, Polysorbate 80, and Hydroxypropyl-Beta-Cyclodextrin for use in General Toxicology Studies
pp. 485-492(8)
Authors: Thackaberry, Evan A.; Kopytek, Stephen; Sherratt, Phillip; Trouba, Kevin; McIntyre, Barry

Diabetogenic Effect of a Series of Tricyclic Delta Opioid Agonists Structurally Related to Cyproheptadine
pp. 493-504(12)
Authors: Codd, Ellen E.; Baker, Judith; Brandt, Michael R.; Bryant, Stewart; Cai, Chaozhong; Carson, John R.; Chevalier, Kristen M.; Colburn, Raymond W.; Coogan, Timothy P.; Dax, Scott L.; DeCorte, Bart; Kemmerer, Michael; LeGrand, Edmund K.; Lenhard, James M.; Leone, Angelique M.; Lin, Ling; Mabus, John R.; McDonnell, Mark E.; McMillian, Michael K.; McNally, James J.; Stone, Dennis J.; Wang, Charles Y.; Zhang, Sui-Po; Flores, Christopher M.

Vascular Smooth Muscle Dysfunction and Remodeling Induced by Ginsenoside Rg3, a Bioactive Component of Ginseng
pp. 505-514(10)
Authors: Lee, Jin-Young; Lim, Kyung-Min; Kim, Sun-Young; Bae, Ok-Nam; Noh, Ji-Yoon; Chung, Seung-Min; Kim, Keunyoung; Shin, Yoo-Sun; Lee, Moo-Yeol; Chung, Jin-Ho

The Oxygen Tension Modulates Acetaminophen-Induced Mitochondrial Oxidant Stress and Cell Injury in Cultured Hepatocytes
pp. 515-523(9)
Authors: Yan, Hui-Min; Ramachandran, Anup; Bajt, Mary Lynn; Lemasters, John J.; Jaeschke, Hartmut

Antiretrovirals Induce Endothelial Dysfunction via an Oxidant-Dependent Pathway and Promote Neointimal Hyperplasia
pp. 524-536(13)
Authors: Jiang, Bo; Khandelwal, Alok R.; Rogers, Lynette K.; Hebert, Valeria Y.; Kleinedler, James J.; Zavecz, James H.; Shi, Weibin; Orr, A. Wayne; Dugas, Tammy R.

Cytochrome P4501A1 Is Required for Vascular Dysfunction and Hypertension Induced by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin
pp. 537-546(10)
Authors: Kopf, Phillip G.; Scott, Jason A.; Agbor, Larry N.; Boberg, Jason R.; Elased, Khalid M.; Huwe, Janice K.; Walker, Mary K.

Erratum
pp. 547-547(1)