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The mission of Toxicological Sciences, the official journal of the Society of Toxicology, is to publish premier peer-reviewed, hypothesis-driven, original research articles in all areas of toxicology. Toxicological Sciences Manuscript Central (ToxSci MC), our online submission system, is located at http://mc.manuscriptcentral.com/toxsci. ToxSci MC facilitates convenient uploading of original and revised manuscripts, as well as online review-ing and intercommunication between authors, editors, and reviewers.

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Volume 88, Number 2, December 2005

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In Vitro Cytotoxicity of Nanoparticles in Mammalian Germ-Line Stem Cell
pp. 285-286(2)
Author: Vinardell, Maria Pilar

A Unifying Concept for Assessing Toxicological Interactions: Changes in Slope
pp. 287-297(11)
Authors: Gennings, C.; Carter, W. H.; Carchman, R. A.; Teuschler, L. K.; Simmons, J. E.; Carney, E. W.

In Silico Methods for Evaluating Human Allergenicity to Novel Proteins: International Bioinformatics Workshop Meeting Report, 23–24 February 2005
pp. 307-310(4)
Authors: Thomas, Karluss; Bannon, Gary; Hefle, Susan; Herouet, Corinne; Holsapple, Michael; Ladics, Gregory; MacIntosh, Sue; Privalle, Laura

Role of CYP2E1 in the Epoxidation of Acrylamide to Glycidamide and Formation of DNA and Hemoglobin Adducts
pp. 311-318(8)
Authors: Ghanayem, Burhan I.; McDaniel, L. Patrice; Churchwell, Mona I.; Twaddle, Nathan C.; Snyder, Rodney; Fennell, Timothy R.; Doerge, Daniel R.

Use of a Rainbow Trout Oligonucleotide Microarray to Determine Transcriptional Patterns in Aflatoxin B1-Induced Hepatocellular Carcinoma Compared to Adjacent Liver
pp. 319-330(12)
Authors: Tilton, Susan C.; Gerwick, Lena G.; Hendricks, Jerry D.; Rosato, Caprice S.; Corley-Smith, Graham; Givan, Scott A.; Bailey, George S.; Bayne, Christopher J.; Williams, David E.

Tsc2 Expression Increases the Susceptibility of Renal Tumor Cells to Apoptosis
pp. 331-339(9)
Authors: Kolb, Todd M.; Duan, Ling; Davis, Myrtle A.

Azoxymethane Is a Genetic Background-Dependent Colorectal Tumor Initiator and Promoter in Mice: Effects of Dose, Route, and Diet
pp. 340-345(6)
Authors: Bissahoyo, Anika; Pearsall, R. Scott; Hanlon, Kathleen; Amann, Vicky; Hicks, Donna; Godfrey, Virginia L.; Threadgill, David W.

Involvement of the Integrin-Linked Kinase Pathway in Hexachlorobenzene-Induced Gender-Specific Rat Hepatocarcinogenesis
pp. 346-357(12)
Authors: Plante, Isabelle; Cyr, Daniel G.; Charbonneau, Michel

Detection of Thyroid System–Disrupting Chemicals Using in Vitro and in Vivo Screening Assays in Xenopus laevis
pp. 367-374(8)
Authors: Sugiyama, Shin-ichiro; Shimada, Naoyuki; Miyoshi, Hiroyuki; Yamauchi, Kiyoshi

Exposure to Polybrominated Diphenyl Ethers (PBDEs): Changes in Thyroid, Vitamin A, Glutathione Homeostasis, and Oxidative Stress in American Kestrels (Falco sparverius)
pp. 375-383(9)
Authors: Fernie, Kim J.; Shutt, J. Laird; Mayne, Greg; Hoffman, David; Letcher, Robert J.; Drouillard, Ken G.; Ritchie, Ian J.

Formulation and Characterization of an Experimental PCB Mixture Designed to Mimic Human Exposure from Contaminated Fish
pp. 400-411(12)
Authors: Kostyniak, Paul J.; Hansen, Larry G.; Widholm, John J.; Fitzpatrick, Rich D.; Olson, James R.; Helferich, Jennifer L.; Kim, Kyung Ho; Sable, Helen J. K.; Seegal, Rich F.; Pessah, Isaac N.; Schantz, Susan L.

In Vitro Cytotoxicity of Nanoparticles in Mammalian Germline Stem Cells
pp. 412-419(8)
Authors: Braydich-Stolle, Laura; Hussain, Saber; Schlager, John J.; Hofmann, Marie-Claude

Arginase Activity Differs with Allergen in the Effector Phase of Ovalbumin- versus Trimellitic Anhydride-Induced Asthma
pp. 420-433(14)
Authors: Greene, Amy L.; Rutherford, Mark S.; Regal, Ronald R.; Flickinger, Gail H.; Hendrickson, Julie A.; Giulivi, Cecilia; Mohrman, Margaret E.; Fraser, Daniel G.; Regal, Jean F.

A Study of the Relationship between Cornea Permeability and Eye Irritation Using Membrane-Interaction QSAR Analysis
pp. 434-446(13)
Authors: Li, Yi; Liu, Jianzhong; Pan, Dahua; Hopfinger, A. J.

Inhibition and Induction of Aromatase (CYP19) Activity by Brominated Flame Retardants in H295R Human Adrenocortical Carcinoma Cells
pp. 447-455(9)
Authors: Cantón, Rocío F.; Sanderson, J. Thomas; Letcher, Robert J.; Bergman, Åke; van den Berg, Martin

Behavioral and Pathological Effects in the Rat Define Two Groups of Neurotoxic Nitriles
pp. 456-466(11)
Authors: Boadas-Vaello, Pere; Riera, Judith; Llorens, Jordi

D-Optimal Experimental Designs to Test for Departure from Additivity in a Fixed-Ratio Mixture Ray
pp. 467-476(10)
Authors: Coffey, Todd; Gennings, Chris; Simmons, Jane Ellen; Herr, David W.

Neurobiological Effects of Bisphenol A May Be Mediated by Somatostatin Subtype 3 Receptors in Some Regions of the Developing Rat Brain
pp. 477-484(8)
Authors: Facciolo, Rosa Maria; Madeo, Maria; Alò, Raffaella; Canonaco, Marcello; Dessì-Fulgheri, Francesco

Effect of Chronic Exposure to Aluminium on Isoform Expression and Activity of Rat (Na+/K+)ATPase
pp. 485-494(10)
Authors: Silva, Virgília S.; Duarte, Ana I.; Rego, A. Cristina; Oliveira, Catarina R.; Gonçalves, Paula P.

Methoxychlor Inhibits Brain Mitochondrial Respiration and Increases Hydrogen Peroxide Production and CREB Phosphorylation
pp. 495-504(10)
Authors: Schuh, Rosemary A.; Kristián, Tibor; Gupta, Rupesh K.; Flaws, Jodi A.; Fiskum, Gary

Low-Level Subchronic Exposure to Wood Smoke Exacerbates Inflammatory Responses in Allergic Rats
pp. 505-513(9)
Authors: Tesfaigzi, Yohannes; McDonald, Jacob D.; Reed, Matthew D.; Singh, Shashibhushan P.; De Sanctis, George T.; Eynott, Paul R.; Hahn, Fletcher F.; Campen, Matthew J.; Mauderly, Joe L.

Effect of N-Acetylcysteine on Lipopolysaccharide-Induced Intra-uterine Fetal Death and Intra-uterine Growth Retardation in Mice
pp. 525-533(9)
Authors: Xu, De-Xiang; Chen, Yuan-Hua; Wang, Hua; Zhao, Lei; Wang, Jian-Ping; Wei, Wei

In Utero and Lactational Exposure to TCDD; Steroidogenic Outcomes Differ in Male and Female Rat Pups
pp. 534-544(11)
Authors: Myllymäki, S. A.; Haavisto, T. E.; Viluksela, M.; Toppari, J.; Paranko, J.

Roles of Exercise and Pharmacokinetics in Cerivastatin-Induced Skeletal Muscle Toxicity
pp. 551-561(11)
Authors: Seachrist, Jennifer L.; Loi, Cho-Ming; Evans, Mark G.; Criswell, Kay A.; Rothwell, Charles E.

Pharmacologic and Toxicologic Evaluation of C. novyi-NT Spores
pp. 562-575(14)
Authors: Diaz, Luis A.; Cheong, Ian; Foss, Catherine A.; Zhang, Xiaosong; Peters, Brock A.; Agrawal, Nishant; Bettegowda, Chetan; Karim, Baktiar; Liu, Guosheng; Khan, Khalid; Huang, Xin; Kohli, Manu; Dang, Long H.; Hwang, Paul; Vogelstein, Ahava; Garrett-Mayer, Elizabeth; Kobrin, Barry; Pomper, Martin; Zhou, Shibin; Kinzler, Kenneth W.; Vogelstein, Bert; Huso, David L.

Chemical Effects in Biological Systems—Data Dictionary (CEBS-DD): A Compendium of Terms for the Capture and Integration of Biological Study Design Description, Conventional Phenotypes, and ‘Omics Data
pp. 585-601(17)
Authors: Fostel, Jennifer; Choi, Danielle; Zwickl, Craig; Morrison, Norman; Rashid, Asif; Hasan, Atif; Bao, Wenjun; Richard, Ann; Tong, Weida; Bushel, Pierre R.; Brown, Roger; Bruno, Maribel; Cunningham, Michael L.; Dix, David; Eastin, William; Frade, Carlos; Garcia, Alex; Heinloth, Alexandra; Irwin, Rick; Madenspacher, Jennifer; Merrick, B. Alex; Papoian, Thomas; Paules, Richard; Rocca-Serra, Philippe; Sansone, Assunta-Susanna; Stevens, James; Tomer, Kenneth; Yang, Chihae; Waters, Michael

Effects of Subchronically Inhaled Carbon Black in Three Species. I. Retention Kinetics, Lung Inflammation, and Histopathology
pp. 614-629(16)
Authors: Elder, Alison; Gelein, Robert; Finkelstein, Jacob N.; Driscoll, Kevin E.; Harkema, Jack; Oberdörster, Günter

Toxicological Effects of Gestational and Lactational Exposure to a Mixture of Persistent Organochlorines in Rats: Systemic Effects
pp. 645-655(11)
Authors: Chu, Ih; Bowers, Wayne J.; Caldwell, Don; Nakai, Jamie; Pulido, Olga; Yagminas, Al; Wade, Michael G.; Moir, David; Gill, Santokh; Mueller, Rudi

CORRECTION
pp. 656-656(1)
Authors: Dillman, James F.; Phillips, Christopher S.

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