Toxicological Sciences

Fritz Haber: 1868–1934
pp. 1-2(2)
Author: Witschi, Hanspeter

Reevaluation of the Cancer Potency Factor of Toxaphene: Recommendations from a Peer Review Panel
pp. 3-16(14)
Authors: Goodman, Jay I.; Brusick, David J.; Busey, William M.; Cohen, Samuel M.; Lamb, James C.; Starr, Thomas B.

Is the Human Carcinogen Arsenic Carcinogenic to Laboratory Animals?
pp. 17-23(7)
Authors: Huff, James; Chan, Po; Nyska, Abraham

Intratracheal Instillation as an Exposure Technique for the Evaluation of Respiratory Tract Toxicity: Uses and Limitations
pp. 24-35(12)
Authors: Driscoll, Kevin E.; Costa, Daniel L.; Hatch, Gary; Henderson, Rogene; Oberdorster, Gunter; Salem, Harry; Schlesinger, Richard B.

Ethane Sulfonate Metabolite of Alachlor: Assessment of Oncogenic Potential Based on Metabolic and Mechanistic Considerations
pp. 36-43(8)
Authors: Heydens, William F.; Wilson, Alan G. E.; Kraus, Lori J.; Hopkins, William E.; Hotz, Kathy J.

Dose Response of Early Effects Related to Tumor Promotion of 2-Acetylaminofluorene
pp. 44-51(8)
Authors: Bitsch, Annette; Hadjiolov, Nikolai; Klöhn, Peter-Christian; Bergmann, Ole; Zwirner-Baier, Iris; Neumann, Hans-Günter

Gabapentin-Induced Mitogenic Activity in Rat Pancreatic Acinar Cells
pp. 52-59(8)
Authors: Dethloff, Lloyd; Barr, Bridget; Bestervelt, Lorelle; Bulera, Steven; Sigler, Robert; LaGattuta, Mark; de la Iglesia, Felix

Apoptosis and P53 Induction in Human Lung Fibroblasts Exposed to Chromium (VI): Effect of Ascorbate and Tocopherol
pp. 60-68(9)
Authors: Carlisle, D. L.; Pritchard, D. E.; Singh, J.; Owens, B. M.; Blankenship, L. J.; Orenstein, J. M.; Patierno, S. R.

A Rapid and Sensitive Reporter Gene that Uses Green Fluorescent Protein Expression to Detect Chemicals with Estrogenic Activity
pp. 69-77(9)
Authors: Miller, S.; Kennedy, D.; Thomson, J.; Han, F.; Smith, R.; Ing, N.; Piedrahita, J.; Busbee, D.

Differential Effects of Microsomal Enzyme Inducers on in Vitro Thyroxine (T₄) and Triiodothyronine (T₃) Glucuronidation
pp. 78-84(7)
Authors: Hood, Alan; Klaassen, Curtis D.

Effect of Micelle Fatty Acid Composition and 3,4,3,4-Tetrachlorobiphenyl (TCB) Exposure on Intestinal [¹⁴C]-TCB Bioavailability and Biotransformation in Channel Catfish in Situ Preparations
pp. 85-96(12)
Authors: Doi, A. M.; Lou, Z.; Holmes, E.; Li, C.-L. J.; Venugopal, C. S.; James, M. O.; Kleinow, K. M.

Low-Dose Whole-Body Irradiation (LD-WBI) Changes Protein Expression of Mouse Thymocytes: Effect of a LD-WBI-Enhanced Protein RIP10 on Cell Proliferation and Spontaneous or Radiation-Induced Thymocyte Apoptosis
pp. 97-106(10)
Authors: Chen, S. L.; Cai, L.; Meng, Q. Y.; Xu, S.; Wan, H.; Liu, S. Z.

Ah Receptor-Based Chemical Screening Bioassays: Application and Limitations for the Detection of Ah Receptor Agonists
pp. 107-115(9)
Authors: Seidel, Shawn D.; Li, Violet; Winter, Greg M.; Rogers, William J.; Martinez, Eugenio I.; Denison, Michael S.

1-Bromopropane, an Alternative to Ozone Layer Depleting Solvents, Is Dose-Dependently Neurotoxic to Rats in Long-Term Inhalation Exposure
pp. 116-123(8)
Authors: Ichihara, Gaku; Kitoh, Junzoh; Yu, Xiaozhong; Asaeda, Nobuyuki; Iwai, Hisakazu; Kumazawa, Toshihiko; Shibata, Eiji; Yamada, Tetsuya; Wang, Hailan; Xie, Zhenlin; Takeuchi, Yasuhiro

Comparative Cholinergic Neurotoxicity of Oral Chlorpyrifos Exposures in Preweanling and Adult Rats
pp. 124-132(9)
Authors: Zheng, Quan; Olivier, Kenneth; Won, Yen K.; Pope, Carey N.

An Evaluation of l-Ephedrine Neurotoxicity with Respect to Hyperthermia and Caudate/Putamen Microdialysate Levels of Ephedrine, Dopamine, Serotonin, and Glutamate
pp. 133-142(10)
Authors: Bowyer, John F.; Newport, Glenn D.; Slikker, William; Gough, Bobby; Ferguson, Sherry A.; Tor-Agbidye, John

Dose-Dependent Alterations in Androgen-Regulated Male Reproductive Development in Rats Exposed to Di(n-butyl) Phthalate during Late Gestation
pp. 143-151(9)
Authors: Mylchreest, Eve; Wallace, Duncan G.; Cattley, Russell C.; Foster, Paul M. D.

Characterization of the Period of Sensitivity of Fetal Male Sexual Development to Vinclozolin
pp. 152-161(10)
Authors: Wolf, Cynthia J.; LeBlanc, Gerald A.; Ostby, Joseph S.; Gray, L. Earl

Relaxant Effects of Aflatoxins on Isolated Guinea Pig Trachea
pp. 162-170(9)
Authors: Abdel-Haq, Hanin; Palmery, Maura; Leone, Maria Grazia; Saso, Luciano; Silvestrini, Bruno

Modeling Normal Aging Bone Loss, with Consideration of Bone Loss in Osteoporosis
pp. 171-188(18)
Author: O'Flaherty, Ellen J.

Ocular Changes in Beagle Dogs following Oral Administration of CGS 24565, a Potential Hypolipidemic Agent
pp. 189-194(6)
Authors: Schiavo, D. M.; Bentley, P.

Effects of Glutaraldehyde in a 2-Year Inhalation Study in Rats and Mice
pp. 195-205(11)
Authors: van Birgelen, Angélique P. J. M.; Chou, Billy J.; Renne, Roger A.; Grumbein, Sondra L.; Roycroft, Joe H.; Hailey, James R.; Bucher, John R.

Diethyldithiocarbamate Enhances Production of Nitric Oxide and TNF- by Lipopolysaccharide-Stimulated Rat Kupffer Cells
pp. 206-214(9)
Authors: Ishiyama, Hironobu; Hoglen, Niel C.; Sipes, I. Glenn

A Robust Structure-Activity Relationship (SAR) Model for Esters that Cause Skin Irritation in Humans
pp. 215-222(8)
Authors: Smith, Jeffrey S.; Macina, Orest T.; Sussman, Nancy B.; Luster, Michael I.; Karol, Meryl H.

Metallothionein-Null Mice Are More Sensitive than Wild-Type Mice to Liver Injury Induced by Repeated Exposure to Cadmium
pp. 223-232(10)
Authors: Habeebu, Sultan S.; Liu, Jie; Liu, Yaping; Klaassen, Curtis D.