MADOR: a new tool to calculate decrease of effective doses in human after DTPA therapy
Authors: Fritsch, P.; Grmy, O.; Hurtgen, C.; Brard, P.; Grappin, L.; Poncy, J. L.
Source: Radiation Protection Dosimetry, Volume 144, Numbers 1-4, 9 March 2011 , pp. 371-375(5)
Publisher: Oxford University Press
Abstract:models have been developed to describe dissolution of Pu/Am/Cm after internal contamination by inhalation or wound, chelation of actinides by diethylene triamine penta acetic acid (DTPA) in different retention compartments and excretion of actinideDTPA complexes. After coupling these models with those currently used for dose calculation, the modelling approach was assessed by fitting human data available in IDEAS database. Good fits were obtained for most studied cases, but further experimental studies are needed to validate some modelling hypotheses as well as the range of parameter values. From these first results, radioprotection tools are being developed: MAnagement of DOse Reduction after DTPA therapy.
Document Type: Research Article
Publication date: 9 March 2011
- RPD publishes peer-reviewed papers covering all aspects of personal and environmental dosimetry and monitoring for both ionising and non-ionising radiations. This includes biological aspects, physical concepts, biophysical dosimetry, external and internal personal dosimetry and monitoring, environmental and workplace monitoring and accident dosimetry and dosimetry related to the protection of patients.