EPR/alanine dosimetry in LDR brachytherapy—a feasibility study
Authors: Schultka, Katarzyna; Ciesielski, Bartlomiej; Serkies, Krystyna; Sawicki, Tomasz; Tarnawska, Zofia; Jassem, Jacek
Source: Radiation Protection Dosimetry, Volume 120, Numbers 1-4, September 2006 , pp. 171-175(5)
Publisher: Oxford University Press
Abstract:In this study, we present the results of in vivo dosimetry, using electron paramagnetic resonance in l-alanine, performed on 13 patients treated for gynaecological cancers. The doses from 137Cs (12 samples) and 192Ir (one sample) brachytherapy sources were determined inside vagina. The detectors had a form of small cellulose capsules tightly filled with crystalline alanine. The positions of the detectors were reconstructed from two orthogonal radiographs. The planned doses were calculated with a computer planning system (PLATO, Nucletron). The relative deviations between planned and measured doses ranged from −23 to +14%. The mean deviation from the prescribed dose was relatively low (−5%) with SD of 10%. The main sources of differences between the measured and calculated doses were attributed to uncertainty in the determination of the detector position inside the patient's body and to uncontrolled changes in the detector position during the treatment.
Document Type: Research Article
Publication date: 2006-09-01
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