Evolution of an organophosphate-degrading enzyme: a comparison of natural and directed evolution

Authors: Yang, H.; Carr, P.D.; McLoughlin, S. Yu; Liu, J.W.; Horne, I.; Qiu, X.; Jeffries, C.M.J.; Russell, R.J.; Oakeshott, J.G.; Ollis, D.L.

Source: Protein Engineering, Volume 16, Number 3, March 2003 , pp. 241-a-241(1)

Publisher: Oxford University Press

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Keywords: bi-substrate reactions; dUMP; hydrogen bond; 5,10-methylenetetrahydrofolate; negative cooperativity

Document Type: Research article

DOI: http://dx.doi.org/10.1093/proeng/gzg030

Publication date: 2003-03-01

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