GPCRDB information system for G protein-coupled receptors

Authors: Horn, Florence; Bettler, Emmanuel¹; Oliveira, Laerte²; Campagne, Fabien³; Cohen, Fred E.; Vriend, Gerrit⁴

Source: Nucleic Acids Research, Volume 31, Number 1, 01 January 2003 , pp. 294-297(4)

Publisher: Oxford University Press

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Abstract:

The GPCRDB is a molecular class-specific information system that collects, combines, validates and disseminates heterogeneous data on G protein-coupled receptors (GPCRs). The database stores data on sequences, ligand binding constants and mutations. The system also provides computationally derived data such as sequence alignments, homology models, and a series of query and visualization tools. The GPCRDB is updated automatically once every 4-5 months and is freely accessible at http://www.gpcr.org/7tm/.

Document Type: Research article

DOI: http://dx.doi.org/10.1093/nar/gkg103

Affiliations: 1: CMBI, University of Nijmegen, The Netherlands 2: Department of Biophysics, EPM, Sao Paulo, Brazil 3: Institute for Computational Biomedicine, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, USA 4: *To whom correspondence should be addressed., Email: vriend@cmbi.kun.nl

Publication date: 2003-01-01

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Nucleic Acids Research (NAR) is a fully Open Access journal, providing rapid publication of leading edge research into the nucleic acids under the following categories: chemistry, computational biology, genomics, molecular biology, nucleic acid enzymes, RNA and structural biology. There is a Survey and Summary section, and methods papers are published
in NAR Methods Online. Each year the first issue is devoted to biological databases, and a later issue to relevant web-based software resources.