Authors: Vaglio, Philippe; Lamesch, Philippe; Reboul, Jérôme; Rual, Jean-François; Martinez, Monica; Hill, David; Vidal, Marc

Source: Nucleic Acids Research, Volume 31, Number 1, 01 January 2003 , pp. 237-240(4)

Publisher: Oxford University Press

Abstract:

WorfDB (Worm ORFeome DataBase; http://worfdb.dfci.harvard.edu) was created to integrate and disseminate the data from the cloning of complete set of ∼19 000 predicted protein-encoding Open Reading Frames (ORFs) of Caenorhabditis elegans (also referred to as the `worm ORFeome'). WorfDB serves as a central data repository enabling the scientific community to search for availability and quality of cloned ORFs. So far, ORF sequence tags (OSTs) obtained for all individual clones have allowed exon structure corrections for ∼3400 ORFs originally predicted by the C. elegans sequencing consortium. In addition, we now have OSTs for ∼4300 predicted genes for which no ESTs were available. The database contains this OST information along with data pertinent to the cloning process. WorfDB could serve as a model database for other metazoan ORFeome cloning projects.

Document Type: Research article

DOI: http://dx.doi.org/10.1093/nar/gkg092

Affiliations: 1: *To whom correspondence should be addressed. , Correspondence may also be addressed to Marc Vidal. Email: marc_vidal@dfci.harvard.edu, Email: philippe_vaglio@dfci.harvard.edu

Publication date: 2003-01-01

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• Nucleic Acids Research (NAR) is a fully Open Access journal, providing rapid publication of leading edge research into the nucleic acids under the following categories: chemistry, computational biology, genomics, molecular biology, nucleic acid enzymes, RNA and structural biology. There is a Survey and Summary section, and methods papers are published
  in NAR Methods Online. Each year the first issue is devoted to biological databases, and a later issue to relevant web-based software resources.

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