Nodular Thickening of Interlobar Fissures: an Early Manifestation of Malignant Mesothelioma: A Case Report

Authors: Shuji Bandoh¹; Jiro Fujita¹; Yoko Fukunaga¹; Shoji Ohtsuka¹; Kentaro Susaki¹; Yu Yang¹; Shoji Kobayashi²; Jiro Takahara¹

Source: Japanese Journal of Clinical Oncology, Volume 31, Number 2, 1 February 2001 , pp. 82-85(4)

Publisher: Oxford University Press

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Abstract:

Two men with occupational exposure to asbestos were admitted to our hospital with minute pleural changes on their chest CT image. Conventional computed tomography (CT) scans of the chest showed slightly thickened interlobar fissures and a small amount of pleural effusion. In addition, high-resolution CT showed small nodular opacities on interlobar fissures. There were no intrapulmonary mass shadows, pleural plaques or other extrapulmonary mass shadows. These roentgenographical findings were very similar to each other. Hyarulonic acid values obtained from their pleural fluid were extremely high. Finally, we diagnosed them as having malignant mesothelioma using an immunocytochemical technique and electronmicroscopy. We conclude that HRCT is helpful in the diagnosis of malignant mesothelioma, particularly in its early manifestation such as nodular opacities of interlobar fissures.

Document Type: Research article

Affiliations: 1: First Department of Internal Medicine and 2: Department of Diagnostic Pathology, Kagawa Medical University, Kagawa, Japan

Publication date: 2001-02-01

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JJCO was established in 1971 as the first journal from Japan to publish clinical research on cancer in English. It was a biannual journal for the first 11 years, and as the number of submissions increased, it became quarterly in 1983 and bimonthly in 1991. Since 1998, the JJCO has been published monthly.