Authors: Chen, Xiaoli; Ni, Renmin; Mo, Yaqin; Li, Lin; Yang, Dongzi

Source: Human Reproduction, Volume 25, Number 5, 22 May 2010 , pp. 1295-1302(8)

Publisher: Oxford University Press

Abstract:

BACKGROUND

This study was designed to establish appropriate body mass index (BMI) level for PCOS women and to compare metabolic abnormalities between PCOS women and control women in Southern China.

METHODS

This clinical cross-sectional study included 999 PCOS patients (857 adults and 142 adolescents) and 922 age-matched controls (742 adults and 180 adolescents).

RESULTS

The proportion of PCOS patients with a BMI above 23 kg/m² was 34.63. Serum insulin, triglycerides, waist and waist/hip (W/H) measurements were all correlated positively with BMI in PCOS women. Prevalence of metabolic syndrome in Chinese PCOS patients was 18.9. Receiver-operating characteristic analysis suggested that at the point of BMI 23 kg/m², the diagnostic power to detect metabolic disorders was at its best.

CONCLUSIONS

PCOS patients with a BMI of 23 kg/m² or beyond may have a higher risk of metabolic disorders. Using an appropriate BMI level may help to improve attention to metabolic disorders among PCOS patients in Southern China.

Keywords: obesity; polycystic ovary syndrome; body mass index; race

Document Type: Research article

DOI: http://dx.doi.org/10.1093/humrep/deq028

Publication date: 2010-05-22

More about this publication?

• Human Reproduction features full-length, peer-reviewed papers reporting original research, clinical case histories, as well as opinions and debates on topical issues. Papers published cover the scientific and medical aspects of reproductive physiology and pathology, endocrinology, andrology, gonad function, gametogenesis, fertilization, embryo development, implantation, pregnancy, genetics, genetic diagnosis, oncology, infectious disease, surgery, contraception, infertility treatment, psychology, ethics and social issues. The highest scientific and editorial standard is maintained throughout the journal along with a rapid rate of publication.

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